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Ubiquitination Governing DNA Repair
DNA damage response (DDR) and lesion repair are vital processes ensuring genome integrity through various pathways depending mainly on the nature of DNA injury and cell cycle stage. DDR is finely regulated at many levels in co-ordination with other ongoing processes as is genome replication and cell cycle progression. Posttranslational modifications (PTMs), affecting both protein-protein and protein-DNA interactions, play a crucial role in finely tuning all processes involved in the restoration of genome lesions. Regarding damaged chromatin, PTMs serve in many cases as recruitment platforms for DNA repair mechanisms by facilitating binding sites or regulating interactions between involved pr...
The Journal of Cell Biology
No. 2, pt. 2 of November issue each year from v. 19 (1963)-47 (1970) and v. 55 (1972)- contain the Abstracts of papers presented at the Annual Meeting of the American Society for Cell Biology, 3d (1963)-10th (1970) and 12th (1972)-
Cholesterol Transporters of the START Domain Protein Family in Health and Disease
Non-vesicular intracellular cholesterol transport is an important mechanism for maintaining membrane cholesterol homeostasis. Recent reports of studies directed at soluble cholesterol transport proteins indicate that aberrant expression of the START proteins may contribute to disease states associated with disorders in cholesterol homeostasis. This is an exciting new direction in the field and the purpose of this book will be to highlight the current research directed at potential roles for the START family in diabetes, cancer and atherogenesis. This book also provides a personal and historical perspective of the discovery-to-publication journey that the authors had for their particular START domain family member. The goal will be to provide perspectives to graduate students, post-doctoral fellows and endocrinology fellows on the research discovery process.
Orphan Monster Spy
"Like Inglourious Basterds for tweens, this clever YA title features Sarah, a blond, blue-eyed Jewish girl in 1939 Germany."--The New York Post After her mother is shot at a checkpoint, fifteen-year-old Sarah finds herself on the run from the Nazis in Third Reich-ruled Germany. While trying to escape, Sarah meets a mysterious man with an ambiguous accent, a suspiciously bare apartment, and a lockbox full of weapons. He's part of the secret resistance against the Reich, and he needs her help. Sarah is to hide in plain sight at a boarding school for the daughters of top Nazi brass, posing as one of them. She must befriend the daughter of a key scientist to gain access to the blueprints for a bomb that could destroy the cities of Western Europe, and steal them. Sarah may look like the rest of the girls, innocent, blonde-haired, and young, but she refuses to become one of the monsters she's surrounded by. She's a brilliant con artist, convincing them she's one of them even as she lives in terror of being found out. And she's determined to get her revenge on them all.
The Discovery of Witches
DigiCat Publishing presents to you this special edition of "The Discovery of Witches" by Matthew Hopkins. DigiCat Publishing considers every written word to be a legacy of humankind. Every DigiCat book has been carefully reproduced for republishing in a new modern format. The books are available in print, as well as ebooks. DigiCat hopes you will treat this work with the acknowledgment and passion it deserves as a classic of world literature.
Directory of Graduate Research
Faculties, publications and doctoral theses in departments or divisions of chemistry, chemical engineering, biochemistry and pharmaceutical and/or medicinal chemistry at universities in the United States and Canada.
Statement of Disbursements of the House as Compiled by the Chief Administrative Officer from ...
Covers receipts and expenditures of appropriations and other funds.
