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The Leydig Cell in Health and Disease
This book provides a comprehensive study of the Leydig cell, a fascinating and important cell type. It presents all of the developments in our understanding of Leydig cell biology and explores a wide variety of current and potential clinical applications. All aspects of Leydig cell biology, development, regulation, and physiology are explored in thirty-one expertly written chapters. This in-depth volume is an invaluable resource.
The Leydig Cell
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Glenn's Urologic Surgery
Glenn's Urologic Surgery is a comprehensive but concise textbook focused on surgical procedures. After more than 30 years it is still required reading for most urology residents and is consulted by practicing physicians while planning surgeries. Chapters are heavily illustrated and progress from diagnosis to indications for surgery, to brief sections on alternative therapies, and then to detailed sections on surgical technique before closing with a discussion of outcomes as found in the literature. The Seventh Edition continues to emphasize laparoscopic procedures. Each section opens with a thoroughly illustrated description of relevant anatomy.
Process Validation in Manufacturing of Biopharmaceuticals
The fourth edition of Process Validation in Manufacturing of Biopharmaceuticals is a practical and comprehensive resource illustrating the different approaches for successful validation of biopharmaceutical processes. A pivotal text in its field, this new edition provides guidelines and current practices, contains industrial case studies, and is expanded to include in-depth analysis of the new Process Validation (PV) guidance from the US FDA. Key Features: Offers readers a thorough understanding of the key concepts that form the basis of a good process validation program for biopharmaceuticals. Includes case studies from the various industry leaders that demonstrate application of these conc...
Campbell-Walsh Urology
Since 1954, Campbell-Walsh Urology has been internationally recognized as the pre-eminent text in its field. Edited by Alan J. Wein, MD, PhD(hon), Louis R. Kavoussi, MD, Alan W. Partin, MD, PhD, Craig A. Peters, MD, FACS, FAAP, and the late Andrew C. Novick, MD, it provides you with everything you need to know at every stage of your career, covering the entire breadth and depth of urology - from anatomy and physiology through the latest diagnostic approaches and medical and surgical treatments. Consult this title on your favorite e-reader with intuitive search tools and adjustable font sizes. Elsevier eBooks provide instant portable access to your entire library, no matter what device you're...
Male Reproductive Toxicology
Methods in Toxicology, Volume 3: Male Reproductive Toxicology, Part A, deals with the male reproductive system and discusses methods that will help identify toxicant-induced changes at all levels in living organisms. It is important to realize that a toxic effect does not occur in a vacuum. All work in toxicology must be predicated on a demonstrated adverse effect in vivo. If good toxicology cannot exist in a vacuum, then there must be a structure. Thus, the book begins by presenting a few models as examples of the ways experiments could be grouped to define the toxicity of a chemical. This is followed by separate chapters on methods such as male mouse sexual behavior test; in vitro techniques for assessing pituitary secretory function; histological methods for preservation of the rat testis; procedures for assessing testicular sperm head counts in mice, rats, and dogs; and guidelines for conducting rodent dominant lethal tests. Subsequent chapters cover topics such as methods for the isolation and purification of Leydig cells from rat and mouse testes, and techniques used in semen analysis and fertility assessment in the rabbit.
Campbell-Walsh Urology 10th Edition Review E-Book
Master the full range of colorectal procedures performed today with Atlas of Surgical Techniques for the Colon, Rectum, and Anus. In this volume in the Surgical Techniques Atlas Series, top authorities provide expert, step-by-step guidance on surgery of the large bowel, rectum, and anus - including both open and closed approaches for many procedures - to help you expand your repertoire and hone your clinical skills. Rely on definitive, expert guidance from the same respected authorities that made Campbell-Walsh Urology the most trusted clinical reference source in the field. Assess and deepen your understanding of key information with answers and rationales for more than 2,800 board-style mu...
Male Hypogonadism
Recent advances in cellular and molecular biology have markedly increased our understanding of normal and abnormal hypothalamic–pituitary–testicular function. Like other volumes in the Contemporary Endocrinology series, the goal of Male Hy- gonadism: Basic, Clinical, and Therapeutic Principles is to link current knowledge of basic biology to the practice of medicine. The development of new methods for testost- one replacement has substantially increased the number of men who are seeking to determine whether they are hypogonadal, and who are using testosterone replacement therapy, thus mandating a broader understanding of testosterone deficiency. The chapters of this book were contributed by authors from around the world, and from various scientific and clinical disciplines, who have devoted their careers to the study of the physiology and pathophysiology of the male. Thus, this comprehensive and focused volume is intended for a wide audience encompassing both basic scientists and practicing clinicians. Its scope will provide a wealth of information for students and fellows as well.
Cellular and Molecular Regulation of Testicular Cells
Conceptual advances in the biological sciences are marked by the applica tion of new techniques and experimental strategies. Nowhere has this ge neric principle been more apparent than in the study of testicular cells, as judged by the evolution of themes presented at the Testis Workshop over the past 23 years. Like its predecessors, the 1995 Testis Workshop was structured to offer fresh insights and approaches for understanding the mechanisms of spermatogenesis and steroidogenesis. The chapters pre sented in this book emphasize three aspects of testicular cell function: first, the molecular analysis of the cell cycle; second, examination of the cell cycle, including the function and identif...
Function of Somatic Cells in the Testis
The papers in this volume represent the proceedings of the XIIth North American Testis Workshop held in Tampa, Florida, April 1993 and put forth recent developments in the study of endocrine and gametogenic functions of the male gonad.
