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Nutritional Toxicology
  • Language: en
  • Pages: 472

Nutritional Toxicology

  • Type: Book
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  • Published: 2002-01-03
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  • Publisher: CRC Press

Nutrients are gaining recognition for their role in protecting against the toxic effects of free radicals, alcohol and other substances. At the same time, advances in food technology, the appearance of novel foods and new ingredients have generated new toxicological issues and forced health and safety professionals to develop new and more reliable

Toxicology of the Skin
  • Language: en
  • Pages: 450

Toxicology of the Skin

  • Type: Book
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  • Published: 2010-02-17
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  • Publisher: CRC Press

This key volume of the Target Organ Toxicology Series provides a fresh and modern approach to the subject of skin toxicology from the perspective of how the skin forms a barrier that protects the body from the external environment and how chemicals and drugs interact with the barrier properties of the skin. Any defects or perturbations to this barr

Reproductive Toxicology, Third Edition
  • Language: en
  • Pages: 512

Reproductive Toxicology, Third Edition

  • Type: Book
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  • Published: 2016-04-19
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  • Publisher: CRC Press

Thoroughly examining the popular and expanding field of reproductive toxicology, this newly revised and expanded third edition provides the latest, cutting-edge scientific developments in this constantly evolving discipline. Reproductive Toxicology’s contributors are experienced regulatory agency and Clinical Research Organization representatives who currently utilize the new techniques discussed in the text and continue to revolutionize reproductive toxicology research. This ground-breaking resource includes: New and important critical mechanistic topics such as epigenetics and omics The first significant compilation of epigenetic mechanisms An in-depth analysis of the role of genomics, proteomics, and metabolomicsin human reproduction New guidelines with respect to the latest research applications in the field

Toxicology of the Nose and Upper Airways
  • Language: en
  • Pages: 450

Toxicology of the Nose and Upper Airways

  • Type: Book
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  • Published: 2016-04-19
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  • Publisher: CRC Press

The application of molecular biologic methods, recognition of neurogenic inflammatory processes, and utilization of genetic knockout animals are just some of the advances in toxicology of the upper airways in recent years. Toxicology of the Nose and Upper Airways presents a culmination of knowledge gained as a result of both human and experimental animal studies over the past decade. With contributions from internationally recognized leaders in the fields of experimental toxicology, respiratory medicine, otolaryngology, allergy, and sensory science, this volume: Examines the effect of selected pollutants on the upper airways of both humans and experimental animals—emphasizing mechanistic i...

Neurotoxicology, Third Edition
  • Language: en
  • Pages: 334

Neurotoxicology, Third Edition

  • Type: Book
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  • Published: 2016-04-19
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  • Publisher: CRC Press

This new edition presents an integrated approach to neurotoxicology, the study of organisms’ responses to changes in their environment and how interruption of the flow of information by chemical exposure causes a wide range of effects – from learning deficits, sensory disturbances in the extremities, and muscle weakness to seizures and signs similar to neurodegenerative disorders such as Parkinson’s or Alzheimer’s disease. It is an essential resource for understanding the sites and mechanisms of neurotoxicity, for formulating testable hypotheses about the effects of neurotoxicants, and for improving the risk assessment process.

Cardiovascular Toxicology, Fourth Edition
  • Language: en
  • Pages: 684

Cardiovascular Toxicology, Fourth Edition

  • Type: Book
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  • Published: 2008-09-04
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  • Publisher: CRC Press

Focused extensively on the toxic effect of chemicals on the cardiovascular system, Cardiovascular Toxicology, Fourth Edition is comprised of several key sections beyond cardio and vascular toxicity, such as principles of myocardial cell injury and key methods of assessing cardiovascular function. New developments include: expanded chapter on passive smoking, which includes adverse effects of smoking, and the effects of secondary smoke new chapter on the negative effects from environmental chemicals on the cardiovascular system chapters covering antibacterial agents and endotoxins include new information on cardiovascular toxicity of antimicrobials, as well as anti-viral agents, antibacterial agents, and other agents

Endocrine Toxicology, Third Edition
  • Language: en
  • Pages: 424

Endocrine Toxicology, Third Edition

  • Type: Book
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  • Published: 2016-04-19
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  • Publisher: CRC Press

With contributions by international experts in academia, chemical manufacturing, government research laboratories, regulatory agencies, and private consulting, this guide explores the potentially damaging influence of environmental agents on the endocrine system. It examines endocrine toxicology’s increased importance in environmental safety issues due to legislative directives established over the past ten years. Covering all principal areas of EPA concern, Endocrine Toxicology, Third Edition provides: putative endocrine disruptors and mechanisms of endocrine toxicity the history and status of the regulatory process mechanisms of toxic effects in various hormonal systems comparisons of the endocrine responses in humans, livestock, and wildlife testing methods in mammalian, fish, avian, and amphibian models valuable insight into the approaches of various personnel in the field, including: government officials who make and oversee policy; scientists in charge of development and validation of testing methods; basic researchers who identify toxic mechanisms; and manufacturers responsible for environmentally benign product certification

Ovarian Toxicology
  • Language: en
  • Pages: 249

Ovarian Toxicology

  • Type: Book
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  • Published: 2013-04-08
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  • Publisher: CRC Press

In recent years, there has been an alarming increase in environmental by-products that may be harmful to ovarian function. Along with this dangerous situation, the modern trend toward delaying motherhood poses immediate concerns regarding the long-term impact of environmental risks on human fertility. The uncertainty of our reproductive future intensifies the need for a single reference that investigates the chemicals with the potential to jeopardize fertility. The only known text that deals specifically with toxicity in the ovary, Ovarian Toxicology updates our current understanding of the effects of environmental chemicals on ovarian function. This new title in the Target Organ Toxicology ...

Development of a Muscle Cell Culture Bioassay for Serum-borne Growth Factors Affecting Protein Turnover
  • Language: en
  • Pages: 632
Biotechnology and Safety Assessment
  • Language: en
  • Pages: 400

Biotechnology and Safety Assessment

  • Type: Book
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  • Published: 2002-09-05
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  • Publisher: Elsevier

A comprehensive treatise on new developments in biotechnology, the authors of Biotechnology and Safety Assessment, 3e, bring readers an up-to-date review of food safety issues, pre-clinical safety and development of new foods and drugs, plant biotechnology, food allergies and safety assessment, and consumer benefits with regard to genetically modified food. Tomorrow's foods will be obtained from genetically modified crops, offering consumers higher nutritional value and more of it. Our medications will be obtained through a variety of biotechnological procedures yielding more potent and specific medications for diseases and vaccines. In order to make this view of the future come to light, Jo...