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The European School of Oncology came into existence to respond to a need for information, education and training in the field of the diagnosis and treatment of cancer. There are two main reasons why such an initiative was considered necessary. Firstly, the teaching of oncology requires a rigorously multidisciplinary approach which is difficult for the Universities to put into practice since their system is mainly disciplinary orientated. Secondly, the rate of technological development that impinges on the diagnosis and treatment of cancer has been so rapid that it is not an easy task for medical faculties to adapt their curricula flexibly. With its residential courses for organ pathologies a...
This textbook combines essential information on clinical cancer medicine with a guide to the latest advances in molecular oncology and tumor biology. Providing a systematic overview of all types of solid tumors, including epidemiology and cancer prevention, genetic aspects of hereditary cancers, differential diagnosis, typical signs and symptoms, diagnostic strategies and staging, and treatment modalities, it also discusses new and innovative cancer treatments, particularly targeted therapy and immunotherapy. Expert commentaries at the end of each chapter highlight key points, offer insights, suggest further reading and discuss clinical application using case descriptions. This textbook is an invaluable, practice-oriented tool for medical students just beginning their clinical oncology studies, as well as for medical oncology residents and young professionals.
Malignant pleural mesothelioma (MPM) is a rare thoracic cancer that derives from the mesothelial cells of the pleura and is causally associated with exposure to asbestos. Because of its aggressiveness and resistance to therapies, MPM prognosis is extremely poor and the 5-year survival rate is approximately 10%. Despite its poor effectiveness, chemotherapy with cisplatin and pemetrexed has long remained the standard-of-care for upfront treatment with no second line therapy available. Recently, the approval of ipilimumab (anti-CTLA-4) plus nivolumab (anti-PD-1) for the first-line treatment of unresectable MPM has marked a significant milestone, in particular for the non-epithelioid MPM subtype...
In response to the pharmaceutical industry’s growing need for new chemicals for drug development, researchers are looking at marine sources for novel bioactive natural products. Oceans are packed with bioactive secondary metabolites, drawing the attention of many scientists across the globe. This new book, Handbook of Research in Marine Pharmaceutics: Exploring Oceanic Microbial Diversity for Human Health and Wellness, presents a range of novel antibacterial, antiviral, and anticancer chemicals identified from marine sources, along with their potential applications in drugs for the eradication and treatment of diseases. The book covers topics such as the use of marine polysaccharides, mari...
A new coronavirus, most likely spilled over from an animal species, has plunged us into the third epidemic of this kind in the last twenty years, against which there were neither vaccines nor therapies.While we argue over the future of humanity, vulnerable to the ecological and environmental degradation that has enabled the pandemic, extraordinary technologies have been developed to combat infectious diseases. In just eleven months it was possible to develop, test and produce the vaccines that are gradually enabling us to escape the SARS-CoV-2 nightmare. In addition, with the legacy of the technologies developed against COVID-19, we will be able to overcome antimicrobial resistance—a slow ...
In this book, readers will get to understand quality and safety issues relating to a myriad of medicinal products not previously covered in a single treatise. These range from traditional medicines, herbal formulations, and health supplements, to modern pharmaceuticals and biopharmaceuticals, to frontier technologies such as recombinant proteins, monoclonal antibodies, novel and traditional vaccines, cells, tissues and gene therapy products. The upstream manufacture and assurance of quality and supply chain integrity for active pharmaceutical ingredients and excipients, as well as their challenges, are being given their due attention here. Quality and safety issues arising from product conta...
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