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Biological Weapons
The threat of biological weapons has been worrying about the armed forces, as well as political leaders for quite some time. With the global recorded deaths from COVID-19 surpassing one million, the biotechnological revolution has heightened the fear of future weaponized pathogens. The COVID-19 virus or its variant could be the most effective weapon for future biological warfare. The indiscriminate effect of such a weapon and its power to cripple economies and devastate the lives of people may make it attractive to rogue States and non-State actors. This book provides an updated analysis of biological warfare agents, including the COVID-19 virus, biotechnological developments affecting biological agents, and the legal regime responsible for preventing the use of biological weapons.
New anti-infective strategies for treatment of tularemia
Francisella tularensis, the causative agent of tularemia, is a paradigm among human pathogens. This Gram-negative bacterium has an intracellular lifestyle, which probably reflects an adaptation to its natural animal and protozoa reservoirs. This is one of the most infectious agents in humans and animals; only a few bacteria are needed to induce a severe infection in both types of hosts. The clinical presentation and severity of human tularemia varies according to the portal of entry of bacteria, the bacterial inoculum, the virulence of the infecting strain, and the immune response of the host. Although most infections occur after direct inoculation of bacteria through the skin (through skin ...
Tularemia: Epidemiology, Ecology, Genomics, Immunity and Pathogenesis
Tularemia is a severe anthropozoonosis caused by Francisella tularensis. The genus Francisella contains five species: F. tularensis, F. philomiragia, F. hispaniensis, F. noatunensis and F. novicida. First described in 1911 in Tulare County, California, it has since been reported worldwide, capable of infecting more than 250 vertebrates and invertebrate species. Although it causes disease in various animal species, no animal has been identified as a main reservoir of this pathogen. Humans acquire infection by several routes, including direct contact with infected animals, ingestion of water or food contaminated by infected animals, exposure to infected arthropod vectors or by inhalation of in...
Biobanking
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Antimicrobial Agents and Intracellular Pathogens
Antimicrobial Agents and Intracellular Pathogens is the first book devoted to the relationships among intracellular pathogens, antibiotics, and cells. The book is divided into two sections. Part One describes the effects of antibiotics on uninfected and infected phagocytic cells, the subcellular location of antibiotic compounds, the subcellular compartment of intracellular microorganisms multiplication, and the vectorization of antibiotics. Part Two focuses on intracellular pathogens used as paradigms, including strict intracellular bacteria and antibiotics such as Chlamydia, Rickettsia, Ehrlichia, and Coxiella burnetii; facultative intracellular bacteria and antibiotics such as Legionella and Mycobacteria; and intracellular protozoa and antimicrobial agents, such as Leishmania, Trypnonosoma, and Toxoplasma. This book will be an important reference for microbiologists, clinical microbiologists, infectious disease experts, and researchers in pharmaceutical companies involved in antibiotic development.
Hunter's Tropical Medicine and Emerging Infectious Disease
Hunter's Tropical Medicine and Emerging Infectious Disease is your comprehensive, go-to resource on the health conditions that arise in the tropics! From infectious diseases through environmental issues, poisoning and toxicology, animal injuries, and nutritional and micronutrient deficiencies, this medical reference book provides you with all the guidance you need to diagnose and manage even the most exotic health concerns. Stay at the forefront of this ever-changing field with Hunter's Tropical Medicine and Emerging Infectious Disease! Understand the common characteristics and methods of transmission for each disease, and learn all the applicable diagnosis, treatment, control, and preventio...
Updates on Brucellosis
Brucellosis is a major zoonotic disease that may cause a serious illness in humans and animals. Global prevalence of human brucellosis remains significant. More than half a million new brucellosis cases from 100 countries are reported annually to the World Health Organization (WHO). The majority of these cases are reported in developing countries.In humans, brucellosis (undulant fever, Malta fever) is characterized by an acute bacteremic phase followed by a chronic stage that may extend over many years and may involve many tissues. It is a systemic disease, and many organ systems (nervous system, heart, skeletal system, bone marrow, etc.) may become involved following hematogenous disseminat...
