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Genome-Wide Association Studies
Experts from academia and industry highlight the potential of genome-wide association studies from basic science to clinical and biotechnological/pharmaceutical applications.
Statistical Analysis of Next Generation Sequencing Data
Next Generation Sequencing (NGS) is the latest high throughput technology to revolutionize genomic research. NGS generates massive genomic datasets that play a key role in the big data phenomenon that surrounds us today. To extract signals from high-dimensional NGS data and make valid statistical inferences and predictions, novel data analytic and statistical techniques are needed. This book contains 20 chapters written by prominent statisticians working with NGS data. The topics range from basic preprocessing and analysis with NGS data to more complex genomic applications such as copy number variation and isoform expression detection. Research statisticians who want to learn about this grow...
The Underlying Mechanisms and Novel Approaches for Diabetes and its Related Complications
Diabetes mellitus is a chronic metabolic disease characterized by elevated blood glucose levels, which severely affects the quality of life and survival of patients. The latest data from the International Diabetes Federation showed that there are approximately 537 million diabetic patients globally in 2021, and it is expected to reach 783 million by 2045. The treatment regime of diabetic patients mainly refers to the management of blood glucose and its complications. At present, typical hypoglycemic medications include insulin and non-insulin hypoglycemic drugs, which can be subdivided into a-glucosidase inhibitors, metformin, thiazolidinediones, sulfonylureas, glinides, DPP-4i, GLP-1RA, and...
Handbook of Statistical Bioinformatics
Now in its second edition, this handbook collects authoritative contributions on modern methods and tools in statistical bioinformatics with a focus on the interface between computational statistics and cutting-edge developments in computational biology. The three parts of the book cover statistical methods for single-cell analysis, network analysis, and systems biology, with contributions by leading experts addressing key topics in probabilistic and statistical modeling and the analysis of massive data sets generated by modern biotechnology. This handbook will serve as a useful reference source for students, researchers and practitioners in statistics, computer science and biological and biomedical research, who are interested in the latest developments in computational statistics as applied to computational biology.
Artificial Intelligence Solutions for Global Health and Disaster Response: Challenges and Opportunities
Artificial intelligence (AI) has shown promise as an effective tool in disaster preparedness and response, providing a unique perspective on some of the most urgent health challenges. Rapid advances in AI technology can potentially revolutionize the way how we respond to emergencies and disasters that affect the world's health, including early warning systems, resource allocation, and real-time decision-making. This Research Topic aims to explore the latest developments in AI and its applications in global health and disaster response, providing a comprehensive overview of the potential and challenges of AI in improving health outcomes in crises. This Research Topic will bring together leading researchers, practitioners, and policymakers in global health and disaster response to share their experiences and insights on how AI can be leveraged to improve response efforts and enhance healthcare delivery.
Aloof CEO's Substitute Sweetheart
Bai Yiyi fell into an abyss after she got entangled with the frightening CEO Helian Hao. In order to protect the Bai Clan's peace of mind, she signed the contract with hatred. The love that He Lianhao had for her had caused her to fall into despair. He realized that he was just a double after all. With a similar face and two different people, who was the true love of Helian Hao?
Into The Sky
Eighteen years ago, a first god body appeared in the Xu family. It had ten divine veins, but the news of it had been leaked out, and ten divine veins had been destroyed. From then on, even though he had the qualifications of a god body, he could no longer cultivate. He had never been known to shake the mountains and rivers; he had never been able to cover the sky with his hands, but he had guided the world; he had never possessed endless abilities, but he had been respected by the world as a teacher; he was destined to not live past twenty, even though he was young and extraordinary.
Waste to Profit
Waste to Profit: Environmental Concerns and Sustainable Development gives information about selecting the most suitable technology for waste treatment and energy recovery under different conditions. It contains techno-economic analysis, life cycle assessment, optimization of tools and technologies, including overview of various technologies involved in the treatment of wastes and factors influencing the involved processes. Finally, it explores the environmental, socioeconomic, and sustainability impact of different waste-to-energy systems. Features: Reviews energy sources and technologies from waste, their environmental interactions, and the relevant global energy policies Provides overview ...
Advanced Intelligent Computing Technology and Applications
This 13-volume set LNCS 14862-14874 constitutes - in conjunction with the 6-volume set LNAI 14875-14880 and the two-volume set LNBI 14881-14882 - the refereed proceedings of the 20th International Conference on Intelligent Computing, ICIC 2024, held in Tianjin, China, during August 5-8, 2024. The total of 863 regular papers were carefully reviewed and selected from 2189 submissions. This year, the conference concentrated mainly on the theories and methodologies as well as the emerging applications of intelligent computing. Its aim was to unify the picture of contemporary intelligent computing techniques as an integral concept that highlights the trends in advanced computational intelligence and bridges theoretical research with applications. Therefore, the theme for this conference was "Advanced Intelligent Computing Technology and Applications". Papers that focused on this theme were solicited, addressing theories, methodologies, and applications in science and technology.
