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Settling
  • Language: en
  • Pages: 285

Settling

What if the real you was the one person your husband couldn’t ever meet? Jane Johansen has carefully crafted a seemingly perfect life. She’s blessed with an adoring husband, Edward, two unwavering best friends, a powerful corporate job, and a high-security penthouse. Then one day, Jane is unceremoniously fired, Edward’s father abruptly dies—and Jane’s painstakingly-built world starts crashing down around her. Edward decides they should move to his North Carolina hometown, and settle into suburbia surrounded by his large, extended family. But Jane knows that she can never truly fit in to this happy world, for she has never explained the truth of her life to Edward. Jane hopes moving...

Help Yourself
  • Language: en
  • Pages: 275

Help Yourself

In a small Southern town, a young woman is about to get some life-changing news . . . Lured away from her small mountain town by the promise of an inheritance from the biological father she never met, Merry Strand heads to a remote barrier island off of North Carolina called Topsail. This sudden and unexpected windfall could save her family from financial ruin. But there’s a catch. Before she can get the money, she needs to complete a regimen of self-improvement tasks. Surrounded by her late father’s lawyer, Fritz (who just wants to go home to London); an uncle who’s hoping to steal her newfound legacy; and a widower staying in the beach house next door, Merry has her work cut out for her and plenty of obstacles in her way. And complicating matters are a crazy radio therapist, a suicidal software engineer, a matchmaking dog, and possibly a ghost . . . Set during the island’s off-season, this lively tale, both poignant and packed with humor, shows how romance can come when you least expect it and how when it comes to improving our lives, we can all use a little help.

Drugs, Addiction, and the Brain
  • Language: en
  • Pages: 351

Drugs, Addiction, and the Brain

Drugs, Addiction, and the Brain explores the molecular, cellular, and neurocircuitry systems in the brain that are responsible for drug addiction. Common neurobiological elements are emphasized that provide novel insights into how the brain mediates the acute rewarding effects of drugs of abuse and how it changes during the transition from initial drug use to compulsive drug use and addiction. The book provides a detailed overview of the pathophysiology of the disease. The information provided will be useful for neuroscientists in the field of addiction, drug abuse treatment providers, and undergraduate and postgraduate students who are interested in learning the diverse effects of drugs of abuse on the brain. Full-color circuitry diagrams of brain regions implicated in each stage of the addiction cycle Actual data figures from original sources illustrating key concepts and findings Introduction to basic neuropharmacology terms and concepts Introduction to numerous animal models used to study diverse aspects of drug use. Thorough review of extant work on the neurobiology of addiction

Introduction to Addiction
  • Language: en
  • Pages: 278

Introduction to Addiction

Introduction to Addiction, Volume One in the series, introduces the reader to the study of neurobiology of addiction by clearly defining addiction and its neuroadaptational views. This volume includes thorough descriptions of the various animal models applicable to the study of addiction, including Animal Models of the Binge-Intoxication Stage of the Addiction Cycle and Animal Models of Vulnerability to Addiction. The book's authors also include a section on numerous neurobiological theories that aid in the understanding of addiction, including dopamine, prefrontal cortex and relapse. Provides neurobiological theories on how addiction works Explains addiction cycle stages of binge, withdrawal and anticipation Reviews the role of dopamine and the frontal cortex in addiction Discusses the neurocircuitry of reward and stress Includes animal models and neuroadaptational views on addiction

Alcohol
  • Language: en
  • Pages: 402

Alcohol

A current survey and synthesis of the most important findings in our understanding of the neurobiological mechanisms of addiction is detailed in our Neurobiology of Addiction series, each volume addressing a specific area of addiction. Alcohol, Volume 3 in the series, explores the molecular, cellular, and neurocircuitry systems in the brain responsible for alcohol addiction using the heuristic three-stage cycle framework of binge/intoxication, withdrawal/negative affect, and preoccupation/anticipation. Outlines the history and behavioral mechanism of action of alcohol relevant to the neurobiology of alcohol addiction Includes neurocircuitry, cellular, and molecular neurobiological mechanisms of alcohol addiction in each stage of the addiction cycle Explores evolving areas of research associated with all three stages of the alcohol addiction cycle, including neurobiological studies of neurodevelopmental effects of early exposure to alcohol, sleep disturbances caused by alcohol, pain interactions with alcohol, sex differences in the response to alcohol, and epigenetic/genetic interactions with alcohol

Opioids
  • Language: en
  • Pages: 426

Opioids

A current survey and synthesis of the most important findings in our understanding of the neurobiological mechanisms of addiction is detailed in our Neurobiology of Addiction series, each volume addressing a specific area of addiction. Opioids, Volume 4 in the series, explores the molecular, cellular and systems in the brain responsible for opioid addiction using the heuristic three-stage cycle framework of binge/intoxication, withdrawal/negative affect, and preoccupation/anticipation. Highlights recent advances in opioid addiction Includes Neurocircuitry, Cellular and Molecular neurobiological mechanisms of opioid addiction Defines opioid abuse and addiction potential, including biological tolerance

Psychostimulants
  • Language: en
  • Pages: 264

Psychostimulants

A current survey and synthesis of the most important findings in our understanding of the neurobiological mechanisms of addiction are detailed in our Neurobiology of Addiction series, each volume addressing a specific area of addiction. Psychostimulants, Volume 2 in the series, explores the molecular and cellular systems in the brain responsible for psychostimulant addiction, including both direct/indirect sympathomimetics and nonsympathomimetics. This volume introduces the readers to the history of psychostimulant use. The authors clearly differentiate the neurobiological effects into three distinct stages of the addiction cycle: binge/intoxication, withdrawal/negative affect, and preoccupation/anticipation. Highlights recent advances in psychostimulant addiction Includes neurocircuitry, cellular and molecular neurobiological mechanisms of psychostimulant addiction Defines the abuse and addiction potentials of both direct and indirect sympathomimetics and nonsympathomimetics

Neurobiology of Addiction
  • Language: en
  • Pages: 576

Neurobiology of Addiction

Neurobiology of Addiction is conceived as a current survey and synthesis of the most important findings in our understanding of the neurobiological mechanisms of addiction over the past 50 years. The book includes a scholarly introduction, thorough descriptions of animal models of addiction, and separate chapters on the neurobiological mechanisms of addiction for psychostimulants, opioids, alcohol, nicotine and cannabinoids. Key information is provided about the history, sources, and pharmacokinetics and psychopathology of addiction of each drug class, as well as the behavioral and neurobiological mechanism of action for each drug class at the molecular, cellular and neurocircuitry level of ...

Nicotine and Marijuana
  • Language: en

Nicotine and Marijuana

A current survey and synthesis of the most important findings in our understanding of the neurobiological mechanisms of addiction is detailed in our Neurobiology of Addiction series, each volume addressing a specific area of addiction. Nicotine and Marijuana, Volume 3 in the Neurobiology of Addiction series, explores the molecular, cellular and systems in the brain responsible for both nicotine and marijuana addiction. This volume includes thorough descriptions of the physiological effects and behavioral effects of nicotine and marijuana addiction. The authors clearly define the neurobiological effects into three distinct steps: Binge/Intoxication Stage, Withdrawal/Negative Affect Stage and last the Preoccupation/Anticipation Stage.

Speak English Like an American for Native Chinese Speakers
  • Language: en
  • Pages: 177

Speak English Like an American for Native Chinese Speakers

If you're a native Chinese speaker wanting to improve your conversational English, this book and audio CD set is for you... What's the secret to speaking English better? It's mastery of those tricky idioms and phrases that are so common in English. And learning these idioms and phrases will not only help you speak better, it'll help you understand Americans better. In this course, you'll join an American family as they go about their day-to-day lives. Along the way, you will master over 300 of today's most common English idioms and expressions! All idioms are defined in both English and Chinese. Discover why thousands of students from around the world are turning to Speak English Like an American to improve their everyday English skills...this book & CD sets is a fun and effective way to improve your English.