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Episodic memory refers to the ability to remember personal experiences in terms of what happened and where and when it happened. Humans are also able to remember the specific perceptions, emotions and thoughts they had during a particular experience. This highly sophisticated and unique memory system is extremely sensitive to cerebral aging, neurodegenerative and neuropsychiatric diseases. The field of episodic memory research is a continuously expanding and fascinating area that unites a broad spectrum of scientists who represent a variety of research disciplines including neurobiology, medicine, psychology and philosophy. Nevertheless, important questions still remain to be addressed. This research topic on the Progress in Episodic Memory Research covers past and current directions in research dedicated to the neurobiology, neuropathology, development, measurement and treatment of episodic memory.
An increase in average life expectancy has given rise to a number of pressing health challenges for the 21st century. Age-related memory loss, whether due to a neurodegenerative condition such as Alzheimer’s disease, or as a product of the normal process of aging, is perhaps the most significant of the health problems of old age presently confronting our society. The Preservation of Memory explores non-invasive, empirically sound strategies that can be implemented to ensure long-lasting and effective retention of information. The chapters in this volume describe and evaluate both well-established and novel methods for improving and strengthening memory, for people with and without dementia...
White matter injury can result from both ischemic and hemorrhagic stroke as well as a host of other CNS diseases and conditions such as neonatal injuries, neurodegenerative disorders including Alzheimer's disease, traumatic brain injuries, carbon monoxide poisoning, and drug or alcohol overdoses. The extent of white matter injury is extremely important to patient outcomes. Several recent technological developments including advanced neuroimaging and the breeding of new rodent models of white matter injury have provided growing insight into initial damage and repair after a stroke or other damaging event. The proposed book will be the first to provide a systematic expert summary of normal white matter morphology as well as white matter injury following stroke and other CNS injuries.
These Proceedings of the 2015 MICCAI Workshop “Computational Diffusion MRI” offer a snapshot of the current state of the art on a broad range of topics within the highly active and growing field of diffusion MRI. The topics vary from fundamental theoretical work on mathematical modeling, to the development and evaluation of robust algorithms, new computational methods applied to diffusion magnetic resonance imaging data, and applications in neuroscientific studies and clinical practice. Over the last decade interest in diffusion MRI has exploded. The technique provides unique insights into the microstructure of living tissue and enables in-vivo connectivity mapping of the brain. Computat...
Are you a Baby Boomer? A member of the post-World War II generation? Retiring or planning to retire at a time when U.S. life expectancy has never been higher? If so, you're part of the exploding population of senior drivers on our highways. You're also helping to create potentially massive problems for our traffic planners, highway safety engineers and healthcare providers who are struggling to cope with the challenge of tens of millions of aging Americans plying the roadways. Or are you? In Drive On! six talented writers – most of them senior drivers themselves – tackle this question head-on. They sort through the many myths and misperceptions about senior drivers. They consult the best...
The world was turned upside down March 2020 by a virus no one expected to turn into a global pandemic. While millions experienced loss and disruption of life, the pandemic put lives on pause, making the nation turn inward to question the life Americans were living pre-pandemic and examine who and what really mattered in this time of financial, emotional, and interpersonal upheaval. Depression, anxiety, violence, substance abuse, and mental health illnesses soared in what became a mental health pandemic. Children lost parents, millions lost jobs, and thousands of teachers and health and wellness professionals abandoned their fields. This has been a tremendous time of reflection on how to be better to ourselves, and to humanity as a whole. What can we learn from this global disruption and how can we become better humans? To start, we can’t look away anymore. The suffering is vast, and the stakes are high. The voices of the pandemic have insightful lessons to teach each and every one of us. It’s time to silence our distractions, listen, and create transformative, sustainable strategies that prioritize the health and wellbeing of humanity.
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Handbook of Medical Image Computing and Computer Assisted Intervention presents important advanced methods and state-of-the art research in medical image computing and computer assisted intervention, providing a comprehensive reference on current technical approaches and solutions, while also offering proven algorithms for a variety of essential medical imaging applications. This book is written primarily for university researchers, graduate students and professional practitioners (assuming an elementary level of linear algebra, probability and statistics, and signal processing) working on medical image computing and computer assisted intervention. - Presents the key research challenges in medical image computing and computer-assisted intervention - Written by leading authorities of the Medical Image Computing and Computer Assisted Intervention (MICCAI) Society - Contains state-of-the-art technical approaches to key challenges - Demonstrates proven algorithms for a whole range of essential medical imaging applications - Includes source codes for use in a plug-and-play manner - Embraces future directions in the fields of medical image computing and computer-assisted intervention
The Neurobiology of Aging and Alzheimer Disease in Down Syndrome provides a multidisciplinary approach to the understanding of aging and Alzheimer disease in Down syndrome that is synergistic and focused on efforts to understand the neurobiology as it pertains to interventions that will slow or prevent disease. The book provides detailed knowledge of key molecular aspects of aging and neurodegeneration in Down Syndrome by bringing together different models of the diseases and highlighting multiple techniques. Additionally, it includes case studies and coverage of neuroimaging, neuropathological and biomarker changes associated with these cohorts. This is a must-have resource for researchers ...