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This is the first book to describe the pharmacological interaction of drugs and exercise with organ systems at molecular and cellular levels. It explains the effect of exercise on pharmacokinetics and pharmacodynamics of drugs, and the activation or induction of antioxidant enzymes which may take place via the adenosine receptor or may occur due to gene expression.
From the moon’s formation, to its potential for future exploration, this richly illustrated volume presents 100 milestones in lunar history. With dazzling images on every spread, and illuminating text by astrobiologist Dr. David Warmflash, Moon: An Illustrated History chronologically presents 100 milestones in the Moon’s development and exploration. Starting 4.5 billion years ago when the Moon formed, this stunning volume moves from the hypotheses of the Moon’s formation (4.5 billion years ago) to sixth-century BCE predictions of solar eclipses, from the twentieth-century Space Race between the US and the Soviet Union to private space companies and possible future lunar colonies. Find out about lunar calendar systems and cults in the Bible; how lunar brightness was used to estimate stellar distances; how advancing telescopes in the seventeenth century allowed us to eye the Moon more closely; how author Jules Verne inspired the Father of Astronautics; the originals of the Saturn V Moon Rocket; the Apollo missions, and so much more.
Throughout history, humans have explored new places, making both good and bad moral decisions along the way. As humanity proceeds to explore space, it is important that we learn from the successes and not repeat the mistakes of the past. This book provides the first comprehensive introduction to ethics as it applies to space exploration and use. It examines real-world case studies that exemplify the ethical challenges we face in exploring beyond Earth: space debris, militarization in space, hazardous asteroids, planetary protection, the search for extraterrestrial life, commercial and private sector activities in space, space settlements, very long duration missions, and planetary-scale interventions. Major themes include human health, environmental concerns, safety and risk, governance and decision-making, and opportunities and challenges of multidisciplinary and international contexts. Ideal for classroom use and beyond, the book provides ways of thinking that will help students, academics and policymakers examine the full range of ethical decisions on questions related to space exploration.
This is the latest book in a series of cardiovascular-related texts from IntechOpen Publishing. The present volume considers general aspects of cardiac disease and is divided into three distinct sections covering cardiac risk, cardiorenal pathology, and novel interventional surgical techniques. The chapters offer insight into the current state of the art with respect to the risks of developing cardiovascular diseases, maintenance of patent vascular access in patients with the cardiorenal syndrome, and a plethora of novel interventional technologies all aimed at salvaging damaged tissue and improving prognosis and reducing mortality. This volume of 18 chapters is intended for general medical and biomedical students at both undergraduate and postgraduate level. It also offers insightful updates on recent advances in the understanding of the pathophysiology of cardiac diseases and the new techniques added to the medical armamentarium to improve the outcomes and prevent mortality and would be of interest to those working in academia and healthcare science.
Taking a science-based look at an emerging area of medicine, Adaptive Biology and Medicine: New Frontiers, Volume 3 discusses the biology of adaptation at the molecular, cellular, and system levels in response to a variety of stressful conditions. Leading international experts present a total of 37 chapters that cover a common continuum of adaptations. For easy reading, the information has been grouped under the sub-headings: Cardiovasular Adaptation, Adaptations to Changes in Altitude and Microgravity, and Environmental Stresses. Examples of cross adaptations are included where repeated exposure to one stimulus may have applications in the treatment and prophylaxis of different diseases. Understanding disease and the mechanisms involved can help us fight disease. When you look at illness through the lens of adaptive biology you can sometimes see medical problems in a new and thought-provoking light. Offering promise for therapeutic strategies in both experimental and clinical pathology, Adaptive Biology and Medicine: New Frontiers explores a new way of thinking about physiological adaptations and their link to disease development.