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Autoantibodies
Autoimmune diseases are characterized by the occurrence of antibodies reacting with self-constituents of the body. The fully updated third edition of Autoantibodies is an in-depth review of the main autoantibodies identified up to now, with particular emphasis on those that display a diagnostic or prognostic clinical value. The new edition covers recent scientific advances, diagnostic techniques, and therapeutic technologies. Each chapter is focused on a single family of autoantibodies. This important reference contains historical notes, definitions, origins and sources of antigens recognized genetic associations, mediated pathogenic mechanisms, methods of detection, as well as clinical util...
Apheresis
Apheresis provides a comprehensive, state-of-the-art review of the applications of apheresis in treating neurologic, hematologic, hepatic and nephrologic disorders. The book deals with the basic science, pathophysiology and role of plasma exchange in treating such disorders as: collagen vascular disease, hypercholesterolemia, demyelating neurologic diseases, myasthenia gravis, multiple sclerosis, glomerulohephritis, myeloma renal failure, vasculitis, fulminant hepatitis, thrombotic angiopathies and acute hepatic failure. The text addresses the various methods and possible complications of plasma exchange and stem cell collection. It offers full coverage of platelet allo-immunization and bone marrow transplantation. The book also explains the specific requirements involved in pediatric apheresis and donor recruitment.
Making Markets for Vaccines
A legacy of our generation -- Ch. 1. We need to invest more in vaccines -- Ch. 2. Promoting private investment in vaccine development -- Ch. 3. A market not a prize -- Ch. 4. Design choices -- Ch. 5. $3 billion per disease -- Ch. 6. Meeting industry requirements -- Ch. 7. How sponsors can do it.
Official Congressional Directory 114th Congress, 2015-2016, Convened January 2015
Directory includes directory information for Congress, including officers, committees, and Congressional advisory boards, commissions and other groups, and legislative agencies; for the Executive branch including the Executive office of the president, each Cabinet agency, independent agencies, commissions and boards; for the Judiciary; for the goverment of the District of Columbia; for selected international organizations; for foreign diplomatic Offices in the United States; and for the Congressional press galleries. Includes also a short statistical section and Congressional district maps.
The Reduction of Drug-Related Harm
The War on Drugs' has traditionally had total abstinence as its target. The contributors to this book take a new and challenging approach to problem drug use, arguing that abstinence is not the only solution. They believe that existing methods of treatment and control have been inadequate in controlling or improving drug problems and they propose a radical alternative: reducing the harm associated with the use of illicit drugs. International in scope, the book covers a broad range of drugs, and of social and individual problems. The spread of HIV infection, which has been described as a greater threat to individual and public health than drug misuse is also considered. The contributors give ...
The Cambridge Handbook of Substance and Behavioral Addictions
Written by leaders in the addictions field, 100 authors from six countries, this handbook is a thoroughly comprehensive resource. Philosophical and legal issues are addressed, while conceptual underpinnings are provided through explanations of appetitive motivation, incentive sensitization, reward deficiency, and behavioral economics theories. Major clinical and research methods are clearly mapped out (e.g. MRI, behavioral economics, interview assessments, and qualitative approaches), outlining their strengths and weaknesses, giving the reader the tools needed to guide their research and practice aims. The etiology of addiction at various levels of analysis is discussed, including neurobiology, cognition, groups, culture, and environment, which simultaneously lays out the foundations and high-level discourse to serve both novice and expert researchers and clinicians. Importantly, the volume explores the prevention and treatment of such addictions as alcohol, tobacco, novel drugs, food, gambling, sex, work, shopping, the internet, and several seldom-investigated behaviors (e.g. love, tanning, or exercise).
Endotoxin in Health and Disease
Offering a basis for further research into the interactions of hosts and pathogens, this work gathers up-to-date findings, and details basic structures, functions and immunology. It provides descriptions of a variety of experimental endotoxin neutralizing agents, as well as a guide to clinical research initiatives and the latest treatments.
Complement Regulatory Proteins
From small beginnings in the early 1970s, the study of complement regulatory proteins has grown in the last decade to the point where it dominates the complement field. This growth has been fueled by the discovery of new regulators, the cloning of old and new regulators, the discovery that many of the regulators are structurally and evolutionarily related to each other and the development of recombinant forms for use in therapy. There are now more proteins known to be involved in controlling the complement system than there are components of the system and the list continues to grow. The time is ripe for a comprehensive review of our current knowledge of these intriguing proteins. This book ...
