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Presenting excellent material for a first course on functional analysis , Functional Analysis in Applied Mathematics and Engineering concentrates on material that will be useful to control engineers from the disciplines of electrical, mechanical, and aerospace engineering. This text/reference discusses: rudimentary topology Banach's fixed point theorem with applications L^p-spaces density theorems for testfunctions infinite dimensional spaces bounded linear operators Fourier series open mapping and closed graph theorems compact and differential operators Hilbert-Schmidt operators Volterra equations Sobolev spaces control theory and variational analysis Hilbert Uniqueness Method boundary elem...
This book introduces mathematicians to real applications from physiology. Using mathematics to analyze physiological systems, the authors discuss models reflecting current research in cardiovascular and pulmonary physiology. In particular, they present models describing blood flow in the heart and the cardiovascular system, as well as the transport of oxygen and carbon dioxide through the respiratory system and a model for baroreceptor regulation. This is the only book available that analyzes up-to-date models of the physiological system at several levels of detail; both simple 'real-time' models that can be directly used in larger systems, and more detailed 'reference' models that show the underlying physiological mechanisms and provide parameters for and validation of simpler models. The book also covers two-dimensional modeling of the fluid dynamics in the heart and its ability to pump, and includes a discussion of modeling wave-propagation throughout the systemic arteries.
The Novartis Foundation Series is a popular collection of the proceedings from Novartis Foundation Symposia, in which groups of leading scientists from a range of topics across biology, chemistry and medicine assembled to present papers and discuss results. The Novartis Foundation, originally known as the Ciba Foundation, is well known to scientists and clinicians around the world.
Development of strategies to assist the movement of poorly permeable molecules across biological barriers has long been the goal of drug delivery science. In the last three decades, there has been an exponential increase in advanced drug delivery systems that aim to address this issue. However, most proprietary delivery technologies that have progressed to clinical development are based on permeation enhancers (PEs) that have a history of safe use in man. This Special Issue entitled “Transmucosal Absorption Enhancers in the Drug Delivery Field” aims to present the current state-of-the-art in the application of PEs to improve drug absorption. Emphasis is placed on identification of novel permeation enhancers, mechanisms of barrier alteration, physicochemical properties of PEs that contribute to optimal enhancement action, new delivery models to assess PEs, studies assessing safety of PEs, approaches to assist translation of PEs into effective oral, nasal, ocular and vaginal dosage forms and combining PEs with other delivery strategies.
International Review of Cell & Molecular Biology presents current advances and comprehensive reviews in cell biology—both plant and animal. Articles address structure and control of gene expression, nucleocytoplasmic interactions, control of cell development and differentiation, and cell transformation and growth. * Authored by some of the foremost scientists in the field * Provides up-to-date information and directions for future research * Valuable reference material for advanced undergraduates, graduate students and professional scientists
Learn about the analytical tools used to characterize particulate drug delivery systems with this comprehensive overview Edited by a leading expert in the field, Characterization of Pharmaceutical Nano- and Microsystems provides a complete description of the analytical techniques used to characterize particulate drug systems on the micro- and nanoscale. The book offers readers a full understanding of the basic physicochemical characteristics, material properties and differences between micro- and nanosystems. It explains how and why greater experience and more reliable measurement techniques are required as particle size shrinks, and the measured phenomena grow weaker. Characterization of Ph...
The strong development in research on grammatical number in recent years has created a need for a unified perspective. The different frameworks, the ramifications of the theoretical questions, and the diversity of phenomena across typological systems, make this a significant challenge. This book addresses the challenge with a series of in-depth analyses of number across a typologically diverse sample, unified by a common set of descriptive and analytic questions from a semantic, morphological, syntactic, and discourse perspective. Each case study is devoted to a single language, or in a few cases to a language group. They are written by specialists who can rely on first-hand data or on material of difficult access, and can place the phenomena in the context of the respective system. The studies are preceded and concluded by critical overviews which frame the discussion and identify the main results and open questions. With specialist chapters breaking new ground, this book will help number specialists relate their results to other theoretical and empirical domains, and it will provide a reliable guide to all linguists and other researchers interested in number.