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Actin-based Motility
Since the discovery of actin by Straub in the 1950’s and the pioneering work of Oosawa on actin self-assembly in helical laments in the 1960’s, many books and conference proceedings have been published. As one of the most essential p- teins in life, essential for movement in organisms rangingfrom bacteria to higher eukaryotes, it is no surprise that actin has fascinated generations of scientists from many different elds. Actin can be considered as a “living treasure” of biology; the kinetics and thermodynamics of self-assembly, the dissipative nature of actin po- merization, the molecular interactions of monomeric and polymerized actin with regulators, the mechanical properties of ac...
Reign of the Buffalo
During the summer months, most parents living in large cities send their kids to camps or summer school. Not Wilson’s parents. For some strange reason, every summer, they send him and his little brother down South to spend time with their Grandmother, an elderly Native American woman living in a small house on the edge of a small town. No one has ever told Wilson the reason his parents continuously send the two boys there. The only thing Wilson knows is that while he's there he's forced to take care of his 100-year-old Great Grandmother. She’s a strange woman that refuses to interact with the public and spends all her days sitting alone, staring into the dark forest at the edge of the backyard. One day when Wilson’s Great Grandmother dies, she leaves him a terrifying gift; one that’s so powerful it alters the way he views the world – and the way the world views him. There are some things parents shouldn't hide from their children.
Demons Winter
Ever been blackmailed into doing something against your will? But then something deep inside tells you, you have to do it anyway? Try being a Shaman and having to save the world, but then get none of the glory or reward for actually winning. Then there's more to it than just being a Shaman: there's millions of people just waiting for you to fail and drop out. But you can't. If you do fail all is lost. No hope, no dreams, no more spirit, and no more life. No pressure right?
The Language of Life
Cooperation requires conversation. Human beings speak to one another. Sounds, scents, and postures allow animals to make their point. While individual cells can't talk, hiss, growl, or bare their teeth, they nevertheless communicate regularly. Their language is based not on words or gestures, but on chemistry â€"using molecules where we would use words, constructing sentences from chains of proteins. The cells that make up the bodies of muticellular organisms inform, wheedle, command, exhort, reassure, nurture, criticize, and instruct each other to direct every physiological function, report every newsworthy event, record every memory, heal every wound. And each of those chemical conversa...
The Immune Synapse
This new collection features the most up-to-date essential protocols that are currently being used to study the immune synapse. Beginning with methods for making biophysical measurements, the volume continues by covering the cell biology of synapses, methods for advanced substrate engineering, mechanobiology topics, new technologies to describe and manipulate synaptic components, as well as methods related to sites of action and immunotherapy. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and fully updated, The Immune Synapse: Methods and Protocols, Second Edition serves as an ideal practical guide for researchers working in this dynamic field. Chapters 5, 11, 18, 27, 30, and 32 are available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.
Screenwriting is Storytelling
While most screenwriting books focus on format and structure, Kate Wright explains how to put story at the center of a screenplay. A compelling story, complete with intriguing characters and situations created with these screenwriting tricks of the trade can become a box office blockbuster film. Screenwriters will learn: - Developing themes within the plot - Using structure to define the story - Creating memorable characters - Establishing moral dilemmas and conflicts - Achieving classic elements of storytelling in a three-act dramatic structure - Mastering different genres
How to Complete a PhD in the Medical and Clinical Sciences
How to Complete a PhD in the Medical and Clinical Sciences provides fresh insight into the PhD process and a concise framework to aid current and prospective students undertaking research in the medical and clinical sciences. Filled with useful hints, tips, and practical guidance, the book covers key topics relevant to a PhD researcher such as publishing and presenting, core principles and techniques in medical science, dealing with common pitfalls, and how to write up and move on. Featuring contributions from authors with experience across the PhD research career spectrum, How to Complete a PhD in the Medical and Clinical Sciences is an invaluable resource for those undertaking their doctoral studies.
Hopkinton
Hopkinton, NY is a quiet little town in the northeast part of the state, settled by New Englanders and built in the New England style with a village green, white wood frame churches, and large Victorian houses. Life here has generally moved at a leisurely pace; yet Hopkinton's people have had their dramas - both comedy and tragic - and their stories have been remembered. In 1903, Carlton Sanford had a book published documenting the settling of the town from a wilderness in 1802 through its first hundred years of development and tracing the descendants of the first settlers. Now Dale Burnett has written a folk history of the second hundred years, chronicling the events in the lives of Hopkint...
The Alcalde
As the magazine of the Texas Exes, The Alcalde has united alumni and friends of The University of Texas at Austin for nearly 100 years. The Alcalde serves as an intellectual crossroads where UT's luminaries - artists, engineers, executives, musicians, attorneys, journalists, lawmakers, and professors among them - meet bimonthly to exchange ideas. Its pages also offer a place for Texas Exes to swap stories and share memories of Austin and their alma mater. The magazine's unique name is Spanish for "mayor" or "chief magistrate"; the nickname of the governor who signed UT into existence was "The Old Alcalde."
