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Research on vitamin C and its effects on cancer is growing in popularity around the world as positive research continues to accumulate building a stronger case for its effectiveness. This concise SpringerBrief on Vitamin C and Cancer presents the latest findings on how vitamin C induces apoptosis. A high concentration of vitamin C allows for ascorbate to generate hydrogen peroxide in tissue that can selectively kill cancer cells. Research has confirmed that high-dose vitamin C is cytotoxic to a wide variety of cancer cell lines, and that it also boosts the anti-cancer activity of several common chemotherapy drugs. Vitamin C also does more than just kill cancer cells. It boosts immunity by stimulating collagen formation to help the body wall off the tumor. It inhibits hyaluronidase, an enzyme that tumors use to metastasize and invade other organs throughout the body. This concise and up-to-date Brief is geared towards cancer researchers and scientists, as well as physicians interested in the basic science and the translational potential of vitamin C in cancer therapeutics.
This unique book – the first ever on bariatric endocrinology – is a comprehensive endocrine and metabolism approach to the diseases that result from excess fat mass accumulation and adipose tissue dysfunction. It takes an approach that places adipose tissue at the center of the clinical approach to patients, as opposed to the complications of adipose tissue accumulation and dysfunction, which has been the dominant approach to date. Initial chapters include discussion of adipose tissue physiology and pathophysiology (adiposopathy), hormonal, central nervous system, and gut microbiome regulation of energy balance and stores, and primary and secondary causes of adipose tissue weight gain. S...
Examines Mexican politics and government from the dictatorship of General Porfirio Dâiaz to the presidency of General Lâazaro Câardenas.
An event of international significance, the California gold rush created a more diverse, metropolitan society than the world had ever known. In Riches for All, leading scholars reexamine the gold rush, evaluating its trajectory and legacy within a global context of religion and race, economics, technology, law, and culture. The opportunity for instant wealth directly influenced a dynamic range of peoples, including Mormon military veterans, California Indian workers, both slave and free African Americans, Chinese village farmers, skilled Mexican miners, and Chilean merchants. Riches for All gives attention to the varying motivations and experiences of these groups and to their struggles with both racial and religious bigotry. Emphasizing gold rush social history, some contributors examine the roles and influence of women, workers, law-breakers, and law-enforcers. Others consider the long-term impact of this episode on California and the American West and on subsequent gold rushes in Pacific Rim countries and the Klondike. With lively and incisive strokes, these historians sketch the most broadly contextualized and nuanced portrait of the California gold rush to date.
Refusing the Favor tells the little-known story of the Spanish-Mexican women who saw their homeland become part of New Mexico. A corrective to traditional narratives of the period, it carefully and lucidly documents the effects of colonization, looking closely at how the women lived both before and after the United States took control of the region. Focusing on Santa Fe, which was long one of the largest cities west of the Mississippi, Deena González demonstrates that women's responses to the conquest were remarkably diverse and that their efforts to preserve their culture were complex and long-lasting. Drawing on a range of sources, from newspapers to wills, deeds, and court records, GonzÃ...
Self Help.
Explains the persistence of violent, unaccountable policing in democratic contexts.
The study of Plato's dialogues has traditionally oscillated between two paradigms: one that portrays the dialogues as treatises expounding doctrines and one that sees them as purely skeptical, rhetorical, or literary. This collection of new essays by twelve noted Plato scholars illustrates the fruitfulness of breaking away from those paradigms, which have divided Platonic scholarship and led it to a number of dead ends. While the essays are diverse in their approaches, each seeks to find a 'third way' to understand Plato, reading him as neither a dogmatist nor a skeptic but as a philosopher capable of reconciling the content and form of his writings.
Newly revised and updated, Mexicanos tells the rich and vibrant story of Mexicans in the United States. Emerging from the ruins of Aztec civilization and from centuries of Spanish contact with indigenous people, Mexican culture followed the Spanish colonial frontier northward and put its distinctive mark on what became the southwestern United States. Shaped by their Indian and Spanish ancestors, deeply influenced by Catholicism, and tempered by an often difficult existence, Mexicans continue to play an important role in U.S. society, even as the dominant Anglo culture strives to assimilate them. Thorough and balanced, Mexicanos makes a valuable contribution to the understanding of the Mexican population of the United States—a growing minority who are a vital presence in 21st-century America.
One Health, the concept of combined veterinary and human health, has now expanded beyond emerging infectious diseases and zoonoses to incorporate a wider suite of health issues. Retaining its interdisciplinary focus which combines theory with practice, this new edition illustrates the contribution of One Health collaborations to real-world issues such as sanitation, economics, food security and vaccination programmes. It includes more non-infectious disease issues and climate change discussion alongside revised case studies and expanded methodology chapters to draw out implications for practice. Promoting an action-based, solutions-oriented approach, One Health: The Theory and Practice of Integrated Health Approaches highlights the lessons learned for both human and animal health professionals and students.