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Presents new information on the mutual interaction of skeletal muscle fibers and motoneurons at all levels, from the physiological to the molecular. Covers genetic, physiological, and hormonal factors affecting skeletal muscle development, control of acetylcholine receptor gene expression, selection and organization of motoneurons, and remodelling and refinement of synaptic inputs under the influence of muscle-derived growth factors. Also discusses the plasticity of the neuromuscular system during regeneration after injury, and in the modification of muscle properties and movement patterns in disease states by changes in sensory input or by electrical stimulation.
Every election provides additional evidence of the continuity of families in American politics. Donn M. Kurtz compiled this collection of articles while conducting research on political families, also hoping to synthesize the body of literature on this subject. The book considers political families as a national, rather than a regional, phenomenon, looking at situations such as children with greater political efficacy and involvement in politics at a younger age. The selections are of an interdisciplinary nature and draw upon several outlets: history, sociology, political science, genealogy, and economics. Contents: Introduction: The Family in Politics, Donn M. Kurtz; Continuity Across Gener...
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This workshop was the second of this series held on the island of santorini in the Cycladic Sea. The first one ("Mechanism of Action of the Nicotinic Acetylcholine Receptor", NATO ASI Se ries H, vol. 10) took place in May 1986 and focused on what was at the time the best studied of all neuroreceptors. This second one, held only two years later, demonstrates the im mense progress achieved since then in the field of neurorecep tors and ion channels. Molecular cloning techniques have now made available the primary structures of a whole array of ion channel proteins, and this in turn has shed light on some gen eral principles of the structure-function relationships of these central elements of intercellular communication. The purpose of this workshop was to explore the common ele ments in gene and protein structure of already cloned ion channel proteins, and to assess the status of other cloning projects in progress. It explicitly focused on very recently published and unpublished results. All participants kept to these goals thereby demonstrating the very value of such work shops for the progress of science.