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Stem Cell Bioprocessing and Manufacturing
The next healthcare revolution will apply regenerative medicines using human cells and tissues. The aim of the regenerative medicine approach is to create biological therapies or substitutes in vitro for the replacement or restoration of tissue function in vivo lost through failure or disease. However, whilst science has revealed the potential, and early products have shown the power of such therapies, there is an immediate and long-term need for expertise with the necessary skills to face the engineering and life science challenges before the predicted benefits in human healthcare can be realized. Specifically, there is a need for the development of bioprocess technology for the successful ...
Germ Cell
This book focuses on the development and biology of germ cell and is edited by Ahmed RG, associate professor and Doctor of Developmental and Experimental Biology, Division of Anatomy and Embryology, Zoology Department, Faculty of Science, Beni-Suef University, Egypt. While many articles have appeared in journals on germ cell, this book provides you with a rare treat - an extensive and intensive study on it. It is one of a kind, offering important and valuable information about the biology of germ cell. This book covers the specification, regulation, and reprogramming of germ cell and germ line stem cells. This book provides important information about the new insight into germ cell signaling and the genotoxic in vitro studies in testicular germ cells. This book offers significant results about the origin, specification, and development of the female germ line in placental mammals and the germ cell tumors and their association with pregnancy.
Heavy-oil and Oil-sand Petroleum Systems in Alberta and Beyond
Hardcover plus CD
Bioreactors for Stem Cell Expansion and Differentiation
An international team of investigators presents thought-provoking reviews of bioreactors for stem cell expansion and differentiation and provides cutting-edge information on different bioreactor systems. The authors offer novel insights into bioreactor-based culture systems specific for tissue engineering, including sophisticated and cost-effective manufacturing strategies geared to overcome technological shortcomings that currently preclude advances towards product commercialization. This book in the fields of stem cell expansion, bioreactors, bioprocessing, and bio and tissue engineering, gives the reader a full understanding of the state-of-art and the future of these fields. Key selling features: Describes various bioreactors or stem cell culturing systems Reviews methods for stem cell expansion and differentiation for neural, cardiac, hemopoietic, mesenchymal, hepatic and other tissues cell types Distinguishes different types of bioreactors intended for different operational scales of tissue engineering and cellular therapies Includes contributions from an international team of leaders in stem cell research
CJChE
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Pluripotent Stem Cells
Stem cells have generated a lot of excitement among the researchers, clinicians and the public alike. Various types of stem cells are being evaluated for their regenerative potential. Marginal benefit resulting by transplanting autologus stem cells (deemed to be absolutely safe) in various clinical conditions has been proposed to be a growth factor effect rather than true regeneration. In contrast, various pre-clinical studies have been undertaken, using differentiated cells from embryonic stem cells or induced pluripotent stem cells have shown promise, functional improvement and no signs of teratoma formation. The scientists are not in a rush to reach the clinic but a handful of clinical st...
Fluidization IX
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Pluripotent Stem Cells
Pluripotent stem cells have distinct characteristics: self-renewal and the potential to differentiate into various somatic cells. In recent years, substantial advances have been made from basic science to clinical applications. The vast amount knowledge available makes obtaining concise yet sufficient information difficult, hence the purpose of this book. In this book, embryonic stem cells, induced pluripotent stem cells, and mesenchymal stem cells are discussed. The book is divided into five sections: pluripotency, culture methods, toxicology, disease models, and regenerative medicine. The topics covered range from new concepts to current technologies. Readers are expected to gain useful information from expert contributors.
In Vitro Methods in Toxicology
The volume brings together the once disparate knowledge of cultural techniques and thus provides an important reference work for industrial and academic toxicologists.
Broken for You
“A dazzling mosaic of intersecting lives and fates . . . Comparisons to John Irving and Tennessee Williams would not be amiss in this show-stopping debut” (Kirkus Reviews, starred review). The national bestseller and Today Show Book Club selection, Broken for You is the story of two women in self-imposed exile whose lives are transformed when their paths intersect . . . When we meet septuagenarian Margaret Hughes, she is living alone in a mansion in Seattle with only a massive collection of valuable antiques for company. Enter Wanda Schultz, a young woman with a broken heart who has come west to search for her wayward boyfriend. Both women are guarding dark secrets and have spent many ye...
