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Peripheral Nerve Disorders: Pathology and Genetics is a definitive, clinically-oriented guide to the pathology of peripheral nerve disorders. These commonly seen neurological challenges have many causes and accurate diagnosis is often necessary via pathological analysis. New techniques exploiting molecular biological knowledge have opened up new vistas to understanding the pathogenesis of these disorders, and hence their effective management. This new title takes a disease-oriented approach to understanding the pathology of these conditions. It combines classical and contemporary techniques to enable practitioners in neurology and neuropathology to better understanding of the disease processes underlying patients’ presentations and to formulate appropriate management plans. Peripheral Nerve Disorders: Pathology and Genetics is a valuable resource for neurologists, neuropathologists, pathologists, neurobiologists and geneticists.
This book examines the complex and paradoxical relationship between authoritarian policing and the social and economic modernization of postwar Germany's largest and most historically "authentic" state, as Bavaria joined the rest of the Federal Republic in a passage from postwar crisis to consumer prosperity.
Strategic corporate finance? This sounds like a paradox at first. After all, corporate finance means responding to the financial markets. Strategy, on the other hand, aims to change and shape the environment in the long term. Lately, though, more and more managers and investors appear to be breaking the laws of the capital market. At the same time, corporations are discovering new ways to not just react to the capital markets, but to actively shape them. The authors show that these violations are not isolated occurrences, but part of a paradigm shift. If companies want to stay successful in changing markets, they have to take a strategic approach to corporate finance. The authors use practical examples to demonstrate how this can be achieved. This book is intended not only for corporate finance experts, but also for students interested in the latest developments on the financial markets.
Fatty acids play an important role in the barrier function of skin and represent a major source of proinflammatory mediators such as prostaglandins, leukotrienes and other lipids in inflammatory skin disorders. This book combines the two major functions of fatty acids in skin biology. In the first part the biosynthesis of fatty acids in skin with its role in barrier function as well as the role of dietary fatty acids on skin cell function and in the treatment of inflammatory skin diseases is presented. The second part deals with skin as a source of proinflammatory eicosanoids, especially with the keratinocyte as a major cellular source. Metabolism of eicosanoids in skin, its role in psoriasis and atopic dermatitis as well as pharmacological inhibition of eicosanoid biosynthesis is reviewed. The book finishes with a chapter describing the methods used for quantification of fatty acids and derivatives in skin inflammation. Anyone interested in skin physiology would benefit from the overviews about the two sites of fatty acids' function in skin integrity and in skin inflammation.
"Hereditary Peripheral Neuropathies" deals with the Charcot-Marie-Tooth group of neuropathies and related primary hereditary neuropathies. The knowledge in this field has grown exponentially during the last ten years. The book is divided into two sections. The first section deals with the clinical presentation, electrophysiological features and differential diagnosis of these disorders as well as with the general biology of the peripheral nerve. The second section gives a detailed account of the known disease entities. The book will be interesting for both the clinician with a special interest in PNS diseases as well as for the researcher.
This new edition of the popular The Strategy Pathfinder updates the micro-cases of real-life problems faced by companies and executives. These micro-cases help readers to engage with the kinds of situations they will encounter in their working lives while provoking discussions about key theoretical themes. Original presentation and design makes this an essential companion for both the business-school classroom and the executive briefcase. The Strategy Pathfinder brings experienced and potential executives alike an instant guide to the concepts and techniques they need to know. An innovative introduction to strategy. Makes readers active “producers” of strategy, rather than passive recipients of received wisdom. Presents essential pathways through the strategy jungle. Each case provokes discussion about a key theoretical theme. Encourages readers to form a view themselves, and then test it against the views of others, before offering recommendations about how best to proceed. Cases are drawn from Africa, the Americas, Asia, Europe and Oceania. Supported by online lecturer supplements.
Women Screenwriters is a study of more than 300 female writers from 60 nations, from the first film scenarios produced in 1986 to the present day. Divided into six sections by continent, the entries give an overview of the history of women screenwriters in each country, as well as individual biographies of its most influential.