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Research in transfusion medicine is diverse and interdisciplinary, involving scientists and physicians in hematology, basic sciences, biology, biotechnology and so forth. It regularly proposes innovation from the donors to the patients along the whole transfusion chain in terms of blood screening, processing and transfusion praxis. The present Research Topic covers recent advances in transfusion medicine and blood, and provides an overview of the current knowledge. It includes original articles, reviews and perspectives for the future challenges.
We identify two motives, prudence and risk aversion, which give rise to precautionary behaviour for a quantity or price setting monopolist facing demand uncertainty who has dual theoretic (DT) preferences. We also analyze a piecewise linear profit function due to a tax on profits which varies with the profit level. We show that the comparative statics of greater risk (mean-preserving spread (MPS) and mean- utility preserving spread (MUPS)) can be totally or partially determined by the Diamond-Stiglitz [1974] and Kihlstrom-Mirman [1974](DSKM) single-crossing property. For example, for a prudent risk averse quantity-setting DT monopolist, a MPS will have the same impact on output under uncertainty as a fall in the state of demand under certainty. Finally, we find that, in contrast to expected utility, a stochastically larger state of demand (first order stochastic dominance) will raise output even if background risk is present.
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The eBook ‘The red cell life-cycle from erythropoiesis to clearance’ continues the discussion of questions like: What are the changes associated with red blood cell maturation, adulthood and senescence? What are the determinants of red blood cell life span and clearance? What are the mechanisms in control of red blood cell mass in healthy humans and patients with various forms of anaemia? Can red blood cells be 'trained' to provide the body with more oxygen during endurance exercises? What are the markers of circulating red blood cell senescence and in cells during storage and transfusion? And what can be learned from various species that developed advanced adaptations to maintain oxygen...
Reprint of the original, first published in 1866.