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Drug Discovery in Africa
Drug discovery originating in Africa has the potential to provide significantly improved treatment of endemic diseases such as malaria, tuberculosis and HIV/AIDS. This book critically reviews the current status of drug discovery research and development in Africa, for diseases that are a major threat to the health of people living in Africa. Compiled by leading African and international experts, this book presents the science and strategies of modern drug discovery. It explores how the use of natural products and traditional medicines can benefit from conventional drug discovery approaches, and proposes solutions to current technological, infrastructural, human resources, and economic challe...
From Hope to Action through Knowledge
Its November 2001. A university in dire straits, financially bankrupt burdening a debt in excess of R100-million, a disillusioned and demoralised staff complement still reeling from the trauma of retrenchments, coupled with an academic project facing collapse as student numbers dwindle by a third to less than 10 000. Is there a future for such an institution, described by some as a ‘basket case’ with very bleak prospects of survival? This was the landscape that confronted the newly-appointed Vice-Chancellor and Chief Executive Officer (CEO) of the University of the Western Cape. Fast forward to December 2014. The CEO retires from office, bestowing upon his successor a financially sound i...
Systema Porifera
Research whilst compiling this book has uncovered a fauna about twice the size as that previously published in the literature and consequently Systema Porifera revises and stabilizes the systematics of the phylum to accommodate this new knowledge in a contemporary framework. Practical tools (key illustrations, descriptions of character) are provided to facilitate the assignment of approximately 680 extant and 100 fossil genera. Systema Porifera is unique making sponge taxonomy widely available at the practical level of classification (genera, families, order). It is a taxonomic revision of sponges and spongiomorphis (such as sphinctozoans and archaeocyathans) based on re-evaluation of type m...
Living Shores
Originally published in 1981, Living Shores was for many years the standard reference for marine science students but was also embraced by a popular market for its fascinating insights into marine and coastal habitats and the life they support. After a long absence, this classic has been revived and thoroughly reworked to incorporate the many dramatic changes that our oceans and coasts have undergone over the past few decades. This book is the fi rst of a two volume set, and examines the di_ erent marine ecosystems and how humankind interacts with them. It discusses the evolution of the sea and continents and looks at the ecology of coastal systems, including intertidal zones, beaches, dunes...
Progress in the Chemistry of Organic Natural Products 100
The volumes of this classic series, now referred to simply as "Zechmeister" after its founder, L. Zechmeister, have appeared under the Springer Imprint ever since the series' inauguration in 1938. It is therefore not really surprising to find out that the list of contributing authors, who were awarded a Nobel Prize, is quite long: Kurt Alder, Derek H.R. Barton, George Wells Beadle, Dorothy Crowfoot-Hodgkin, Otto Diels, Hans von Euler-Chelpin, Paul Karrer, Luis Federico Leloir, Linus Pauling, Vladimir Prelog, with Walter Norman Haworth and Adolf F.J. Butenandt serving as members of the editorial board. The volumes contain contributions on various topics related to the origin, distribution, ch...
The Fishy Smiths
The discovery of the modern-day coelacanth will forever be linked with the name of JLB Smith. An intense, irascible, eccentric man, JLB (as he was widely known) and his long-suffering wife Margaret were both remarkable South African scientists who changed the course of the biological sciences. Best known for their research on the coelacanth, they also contributed in many other ways to the scientific study of fishes (ichthyology) and related fields. The first comprehensive biography about JLB and Margaret Smith. Traces their formative years and serendipitous meeting, leading up to the discovery of the coelacanth, and the tumultuous years that followed. Details their punitive work ethic, eccen...
Biodiversity and Traditional Knowledge
Biodiversity research and prospecting are long-standing activities taking place in a new legal and ethical environment. Following entry into force of the Convention on Biological Diversity in 1993, and other recent policy developments, expectations and obligations for research and prospecting partnerships have changed. However, to date there are few guides to integrating these concepts with practice. This book offers practical guidance on how to arrive at equitable biodiversity research and prospecting partnerships. Drawing on experience and lessons learned from around the world, it provides case studies, analysis and recommendations in a range of areas that together form a new framework for...
Michael John Davies
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