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Extrasynaptic transmission is a unifying term for a wide variety of cellular processes, in which outside of synaptic terminals transmitter substances activate extrasynaptic receptors. Whereas “synaptic transmission” immediately refers to a process occurring at nerve terminals in which the arrival of a presynaptic impulse evokes exocytosis followed by a postsynaptic response within a millisecond time scale, extrasynaptic transmission has a wide diversity of ultrastructural and therefore mechanistic associated phenomena. In comparison to synaptic, extrasynaptic exocytosis may last for seconds or even minutes, thus expanding the timing of neuronal signaling. Extrasynaptic transmission has n...
How hormonal signals in one small structure of the brain—the hypothalamus—govern our physiology and behavior. As human beings, we prefer to think of ourselves as reasonable. But how much of what we do is really governed by reason? In this book, Gareth Leng considers the extent to which one small structure of the neuroendocrine brain—the hypothalamus—influences what we do, how we love, and who we are. The hypothalamus contains a large variety of neurons. These communicate not only through neurotransmitters, but also through peptide signals that act as hormones within the brain. While neurotransmitter signals tend to be ephemeral and confined by anatomical connectivity, the hormone signals that hypothalamic neurons generate are potent, wide-reaching, and long-lasting. Leng explores the evolutionary origins of these remarkable neurons, and where the receptors for their hormone signals are found in the brain. By asking how the hypothalamic neurons and their receptors are regulated, he explores how the hypothalamus links our passions with our reason. The Heart of the Brain shows in an accessible way how this very small structure is very much at the heart of what makes us human.
Siskiyou County Library has vol. 1 only.
"For most economists, labor is simply a commodity, bought and sold in markets like any other - and what happens after that is not their concern. Individual prospective workers offer their services to individual employers, each acting solely out of self-interest and facing each other as equals. The forces of demand and supply operate so that there is neither a shortage nor a surplus of labor, and, in theory, workers and bosses achieve their respective ends. Michael D. Yates, in Work Work Work: Labor, Alienation, and Class Struggle, offers a vastly different take on the nature of the labor market. This book reveals the raw truth: The labor market is in fact a mere veil over the exploitation of...
Each year, more than one million people and their loved-ones arrive at a decision to cease attempts at curative medical treatments and shift to hospice care, while one-in-five Americans now live in in geographical regions that have established lawful protocols allowing medical aid in dying—also known as assisted suicide. In this powerful new work, Lew Cohen, a psychiatrist and palliative medicine researcher, reveals a self-determination movement that empowers people to shape the timing and circumstances of their deaths, decriminalizes laws threatening those who help them, and passes assisted dying legislature. He offers a vivid tapestry woven from the candid, inspirational, and graphic sto...
Every year since 1976, Project Censored, our nation's oldest news-monitoring group--a university-wide project at Sonoma State University founded by Carl Jensen, directed for many years by Peter Phillips, and now under the leadership of Mickey Huff--has produced a Top-25 list of underreported news stories and a book, Censored, dedicated to the stories that ought to be top features on the nightly news, but that are missing because of media bias and self-censorship. Seven Stories Press has been publishing this yearbook since 1994, featuring the top stories listed democratically in order of importance according to students, faculty, and a national panel of judges. Each of the top stories is pres...