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Non-coding Rna Transcripts In Cancer Therapy: Pre-clinical And Clinical Implications
'Non-coding RNA Transcripts in Cancer Therapy: Pre-clinical and Clinical Implications' provides a new insight towards role of non-coding RNAs molecules including microRNAs, long non-coding RNAs and circular RNAs in cancer. The reason of focusing on cancer is that this malignant disease is responsible for high death around the world and after cardiovascular diseases, it is a leading cause of death. In the current book, the basic information and knowledge about ncRNAs, their biogenesis and their biological functions are covered. It is shown that ncRNAs can regulate expression level of genes at transcriptional and post-transcriptional levels and therefore, ncRNAs are master and key players in m...
Mitochondrial Intoxication
Mitochondrial Intoxication explores the effects toxic molecules can have upon mitochondrial physiology in the human body. Each chapter is dedicated to a specific toxicant, including pollutants, food additives, illicit and pharmaceutical drugs, and heavy metals. This book considers the implications and impact these have upon mitochondria and the diseases that can result from dysfunction and impairment in the human body. Furthermore, the book provides an overview of mitochondrial physiology and assesses the advances and challenges in testing mitochondrial toxicity. Case studies exploring mitochondrial intoxication in pregnancy and in the geriatric population are also included. This is a comprehensive reference on the main toxicants impacting mitochondria in the human body, and the consequences this can have for health and disease. - Features a wide range of toxicants and their effects on mitochondrial physiology - Covers molecular markers of mitochondrial intoxication - Includes case studies that illustrate the health impacts of toxicity upon mitochondria - Considers future directions regarding the study of mitochondrial intoxication
Body Recomposition
Obesity is a global pandemic rising beyond the status of a lifestyle disorder, and its consequences include impaired metabolism, energy disruption, and abdominal fat deposition and storage. Body Recomposition: A Comprehensive and Metabolic Alternative to Weight Loss presents information on body recomposition, which emphasizes the approach of losing fat while gaining muscle. It contains vast research on topics including factors that influence fat accumulation, strategies for weight management, healthy diet and eating patterns, physical exercise, and lifestyle strategies in healthy weight management. Features: Influence of non-alcoholic fatty liver disease (NAFLD) on stored fat accumulation an...
Natural Products and Human Diseases
Natural products have a long history of use as folk medicines in several systems of traditional medicine. Extensive evidence from modern pharmacological studies has confirmed traditional applications, and unveiled the vast potential of naturally occurring compounds, particularly plant-derived phytochemicals, in the management of chronic human diseases. The past decade has witnessed a surge of findings from randomized controlled trials testifying the safety and efficacy of natural products as adjuncts or alternatives to standard-of-care medications for several illnesses. Biomolecular studies have unveiled hundreds of cellular and molecular targets for phytochemicals including key transcriptio...
Plant Derived Bioactive Compounds in Human Health and Disease
This book offers a comprehensive review of the multifaceted role of phytochemicals in promoting human health and combating diseases. The initial chapters introduce phytochemicals, navigate the natural health landscape, and provide a foundational understanding of these bioactive compounds. The book unfolds the role of phytochemicals as a formidable defense against oxidative stress and explores the unique health benefits and nutritional significance of phytochemicals found in fruit peels. The subsequent chapters further discuss the therapeutic potential of phytochemicals, detailing their role in combating multidrug-resistant bacterial infections and modulating critical pathways in inflammation...
Novel Phytopharmaceutical for Management of Disorders
Novel Phytopharmaceutical for Management of Disorders covers recent advances surrounding phytopharmaceuticals and their potential uses in the management of several disorders as well as in cosmetic benefits. Sections cover the concepts of phytopharmaceuticals and current highlights in disease management. This book also emphasizes phytopharmaceutical drug delivery studies in vivo–in vitro study to various target organs like lungs, liver, and brain. This book provides key information for everyone interested in disease management, drug discovery, and delivery, including medicinal chemists, cosmetic experts, nutritionists, toxicologists, drug formulators, and health care professionals. Students...
