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Sex differences in immunometabolism, prophylaxis and therapy
Immune system function and metabolism are profoundly intertwined on a whole-body and cellular level. This is reflected in both homeostatic processes during growth and development and in pathological states. For instance, chronic inflammation in adipose tissue is a strong predictor of insulin resistance and metabolic syndrome, overall increasing risk for type 2 diabetes and associated co-morbidities in obese individuals. Simultaneously, increased visceral adiposity is linked with a delayed or deficient immune response to infection. On the cellular level, immune cell phenotype is intimately connected with metabolic status. In states of high energy demand immune cells rely on glycolysis for producing ATP, while oxidative phosphorylation is the preferred energy source in resting and regulatory states.
Stochastic Processes, Statistical Methods, and Engineering Mathematics
The goal of the 2019 conference on Stochastic Processes and Algebraic Structures held in SPAS2019, Västerås, Sweden, from September 30th to October 2nd 2019, was to showcase the frontiers of research in several important areas of mathematics, mathematical statistics, and its applications. The conference was organized around the following topics 1. Stochastic processes and modern statistical methods,2. Engineering mathematics,3. Algebraic structures and their applications. The conference brought together a select group of scientists, researchers, and practitioners from the industry who are actively contributing to the theory and applications of stochastic, and algebraic structures, methods,...
Europe by Sleeping Car
Michael Patterson takes the reader on a charming illustrated nostalgic jaunt across Europe by sleeper.
From Helsinki to Belgrade
After the heads of state and government of almost all European countries, the USA, and Canada signed the Final Act of the Conference on Security and Cooperation in Europe in Helsinki on August 1st, 1975, little was heard about the CSCE process. However, far away from the headline-grabbing meetings between the leading politicians of the USA and the USSR as well as the Geneva negotiations on disarmament, the Helsinki process proved to be an efficient framework for the East-West negotiations. The inconclusive Belgrade CSCE Meeting of 1977-1978 - after six months the delegations were only able to agree on a brief final document - was nevertheless a significant milestone for the CSCE process itself: negotiation rules were drawn up, interpreted, negotiated and re-negotiated. The contributions to this volume offer solid insights into the follow-up meeting in Belgrade in 1977/78, the Cold War, and in particular the CSCE process.
Culture: urban future
Report presents a series of analyses and recommendations for fostering the role of culture for sustainable development. Drawing on a global survey implemented with nine regional partners and insights from scholars, NGOs and urban thinkers, the report offers a global overview of urban heritage safeguarding, conservation and management, as well as the promotion of cultural and creative industries, highlighting their role as resources for sustainable urban development. Report is intended as a policy framework document to support governments in the implementation of the 2030 Agenda for Sustainable Urban Development and the New Urban Agenda.
Cultural Sustainable Tourism
This book is an assemblage of diverse yet homogenous research papers that bring together the issues and challenges of cultural heritage conservation and tourism sustainability. The richness of this book stems from its inclusion of diverse case studies from around the globe while scrutinizing the cases of both deterioration and sustainability of cultural heritage belonging to different eras. This book sheds light on the connections between culture as an essential dimension of local sustainability and cultural dimensions of sustainable tourism, further contributing to the complex discussion between culture and tourism. This book gives an overview of current research and subjects of discussion that focuses on cultural sustainable tourism through several sections, such as planning and management of sustainable tourism, sustainable cultural tourism development in a digital era, social and economic impacts of cultural tourism, and sustainable tourism development in urban areas
