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Mir Hardware Heritage
The heritage of the major Mir complex hardware elements is described. These elements include Soyuz-TM and Progress-M ; the Kvant, Kvant 2, and Kristall modules ; and the Mir base block. Configuration changes and major mission events of Salyut 6, Salyut 7, and Mir multiport space stations are described in detail for the period 1977-1994. A comparative chronology of U.S. and Soviet/Russian manned spaceflight is also given for that period. The 68 illustrations include comparative scale drawings of U.S. and Russian spacecraft as well as sequential drawings depicting missions and mission events.
Shuttle-Mir
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The Story of Space Station Mir
* Details how a succession of Salyut space stations led to the development of Mir. * Depicts Mir’s assembly piece by piece, in space, between 1982 and 1996. * Describes how Mir became an international research laboratory. * Advises how Mir technology went on to form the ‘core modules’ of the ISS. * The definitive account of Mir throughout its life through to de-orbiting in March 2001.
The Readers of Novyi Mir
In the “Thaw” following Stalin’s death, probing conversations about the nation’s violent past took place in the literary journal Novyi mir (New World). Readers’ letters reveal that discussion of the Terror was central to intellectual and political life during the USSR’s last decades. Denis Kozlov shows how minds change, even in a closed society.
Mir??t Al-quds (Mirror of Holiness): A Life of Christ for Emperor Akbar
Akbar’s commission of a Life of Christ from the Jesuit Jerome Xavier resulted in a fascinating text (1602) in which the author’s concern not to antagonize his Muslim hosts is apparent. The 27 miniatures were inspired by the text itself, resulting in unique interpretations of episodes that often do not find parallels in a European context.
Current Perspectives in microRNAs (miRNA)
Nearly 97% of the human genome is the non-coding DNA, which varies from one species to another, and changes in these sequences are frequently noticed to manifest clinical and circumstantial malfunction. Numerous non-protein-coding genes are recently found to encode microRNAs, which are responsible for RNA-mediated gene silencing through RNA interference (RNAi)-like pathways. MicroRNAs (miRNAs), small single-stranded 17–25 nucleotide RNAs capable of interfering with intracellular messenger RNAs (mRNAs) that contain either complete or partial complementarity, are useful for the design of new therapies against cancer polymorphism and viral mutation. Currently over 1000 native miRNA species fo...
Tumors of the Central Nervous system, Volume 3
The classification of brain tumors is up-dated using magnetic resonance spectroscopy technology. The role of cellular immortality in brain tumors is reviewed. Tumor to tumor metastases are a common occurrence; for example, , brain metastasis from breast cancer, lung cancer, and renal cancer is discussed. Genetic profiling and treatment (including neurosurgery) of such brain cancers are explained. Breast cancer patients treated with certain drugs (e.g., capecitabine and lapatinib can develop CNS tumors. Role of brain tumor suppressor genes (e.g., NRP/B gene) is pointed out. Biomarkers used to diagnose brain malignancies are explained in detail. A number of imaging modalities used for diagnosing and assessing the effectiveness of treatments of brain tumors are presented. The imaging methods discussed include MRI, PET, CT, MRSi, and SPECT. Also, is discussed the impact of PET using radiolabeled amino acids on brain tumors.
Terahertz (THz), Mid Infrared (MIR) and Near Infrared (NIR) Technologies for Protection of Critical Infrastructures Against Explosives and CBRN
Critical infrastructures are targets for terrorism and deliver a valuable vector through which the proliferation of CBRN and explosive precursors can be detected. Recent technological breakthroughs, notably in the field of near infrared (NIR), mid infrared (MIR), Terahertz (THz) and Gigahertz (GHz) sources and detectors, have led to rugged commercial devices, capable of standoff sensing a range of these dangerous substances. However, at the same time criminal and terrorist organizations have also benefited from the availability of technologies to increase the threat they pose to the security of citizens and a concerted effort is needed to improve early detection measures to identify activiti...
MicroRNAs in Cancer Translational Research
MicroRNA (miRNA) is a cutting-edge topic in the scientific and medical fields. This is a timely and specialized book focusing on the current understanding of miRNAs and the potential for their application in cancer diagnosis, prognosis, and therapeutic targets. It also provides discussion of the lessons learned from translational miRNA studies and exploration of the next steps required to advance this field. The unique book comprises 22 in-depth chapters by gathering unparalleled topics of interest in miRNAs by international team of world-renowned experts in the field. The first fifteen chapters provide comprehensive and expert perspectives on the most common cancers from bench to bedside ap...
