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Willett's Nutritional Epidemiology has become the foundation of this field. This new edition updates existing chapters and adds new ones addressing the assessment of physical activity, the role of genetics in nutritional epidemiology, and the interface of this field with policy.
Overview of Nutritional Epidemiology; Foods and Nutrients; Nature of Variation in Diet; Short Term Dietary Recall and Recording Methods; Food Frequency Methods; Reproducibility and Validity of Food Questionnaries; Recall of Remote Diet; Surrogate Sources of Dietary Information; Anthropometric Measures and Body Composition; Implications of Total Energy Intake for Epidemiologic Analyses; Correction for the Effects of Measurement Error; Vitamin A and Lung Cancer; Dietary Fat and Breast Cancer; Diet and Coronary Heart Disease; Future Research Directions.
This book is an expanded version of the Kahn's widely used text, An Introduction to Epidemiologic Methods (Oxford, 1983). It provides clear insight into the basic statistical tools used in epidemiology and is written so that those without advanced statistical training can comprehend the ideas underlying the analytical techniques. The authors emphasize the extent to which similar results are obtained from different methods, both simple and complex. To this edition they have added a new chapter on "Comparison of Numerical Results for Various Methods of Adjustment" and also one on "The Primacy of Data Collection." New topics include the Kaplan-Meier product-limit method and the Cox proportional hazards model for analysis of time-related outcomes. An appendix of data from the Framingham Heart Study is used to illustrate the application of various analytical methods to an identical set of real data and provides source material for student exercises. The text has been updated throughout.
This is the second edition of the first book to provide a complete picture of the design, conduct and analysis of observational studies, the most common type of epidemiologic study. Stressing sample size estimation, sampling, and measurement error, the authors cover the full scope of observational studies, describing cohort studies, case-control studies, cross-sectional studies, and epidemic investigation. The use of statistical procedures is described in easy-to-understand terms.
Occupational epidemiology has emerged as a distinct subdiscipline of epidemiology and occupational medicine, addressing fundamental public health and scientific questions relating to the specification of exposure-response relationships, assessment of the adequacy of occupational exposure guidelines, and extrapolation of hazardous effects to other settings. This book reviews the wide range of principles and methods used in epidemiologic studies of working populations. It describes the historical development of occupational epidemiology, the approaches to characterizing workplace exposures, and the methods for designing and implementing epidemiologic studies. The relative strengths and limitations of different study designs are emphasized. Also included are more advanced discussions of statistical analysis, the estimation of doses to biological targets, and applications of the data derived from occupational epidemiology studies to disease modeling and risk assessment. The volume will serve both as a textbook in epidemiology and occupational medicine courses and as a practical handbook for the design, implementation, and interpretation of research in this field.
"Comprehensive and comprehensible, but also encouraging -- informed by the hope and belief that informed its creation." -Cancer Amid sweeping advances in the science and treatment of cancer, the TEXTBOOK OF CANCER EPIDEMIOLOGY offers students and professionals a definitive, systematic resource for understanding the factors affecting all types of human cancer. This fully updated new edition offers an overview of epidemiology's key concepts and methods as they relate to cancer (including the emerging potential of biomarkers) as well as site-specific chapters on individual cancers' natural history, pathology, descriptive epidemiology, and etiology. Taken together, these chapters forge connections between established science and the ongoing evolution of this dynamic field. Crisply and concisely written by an assembly of internationally recognized researchers, the TEXTBOOK OF CANCER EPIDEMIOLOGY offers a superlative introduction to the subject's consensuses and controversies for those embarking on their careers and a ready reference for seasoned professionals.
This book combines applied and theoretical approaches to the analysis of epidemiologic issues. It goes beyond elementary material to deal with real problems generated by disease data, and delves into less usual areas such as the analysis of spatial distributions, survival data, proportional hazards regression, and "computer-intensive" approaches to statistical estimation. Each method discussed in the text is illustrated with examples which include complete sets of data. Using actual data demonstrates the strengths and weaknesses of different analytic approaches in describing a disease process. The goal of the book is to allow the reader to develop a clear understanding of analytic approaches...
The classic, definitive guide to the design, conduct, and analysis of randomized clinical trials.
Examining the principles and methods of research on the evaluation of factors affecting the outcome of illness, this volume emphasizes diagnostic and therapeutic interventions--the factors most readily modified by health care providers. The author discusses various ways of structuring observations on patient groups, and appraises the nature and strength of inferences drawn from those observations. Weiss also demonstrates how the results of this type of research--clinical epidemiologic research--can be incorporated into the decision-making process utilized in clinical medicine. The Second edition differs from the earlier one in a number of respects. It now employs a broader frame of reference...
The complex relationships between diet and the major diseases of western civilization are the subject of this volume. It is aimed both at researchers and general readers of the often confusing scholarly literature on the subject.