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Electron Paramagnetic Resonance
Electron Paramagnetic Resonance (EPR) Volume 17 highlights major developments in this area reported up to the end of 1999, with results being set into the context of earlier work and presented as a set of critical yet coherent overviews. The topics covered describe contrasting types of application, ranging from biological areas such as EPR and ENDOR studies of metalloproteins and evidence of free-radical reactions in biology and medically-related systems, to experimental developments and applications involving EPR imaging, the use of very high fields, and time-resolved methods. Critical reviews of applications involving bacterial photosynthesis, spin-labelling and spin-probes studies of self...
Designing Multi-target Drugs
Written by world-renowned experts, this is the first book to gather together knowledge and experiences of the rational discovery of multi-target drugs. It describes the current state of the art, the achievements, and the challenges of the field and lessons learned by researchers.
Progress in Medicinal Chemistry
This volume provides reviews of six topics demonstrating the breadth of the field and recent successes in medicinal chemistry. Each of the first five chapters takes an important biochemical target as its theme and provides an insight into current progress in drug design. The last chapter focuses on the vital subject of pharmacokinetics and the great strides that have been made in this discipline during the past decade. All chapters provide an insight into the skills required of the modern medicinal chemist, in particular, the use of an appropriate selection of the wide range of tools now available to solve key scientific problems.*Presents the latest research in the field of drug discovery *Publishes on a twice yearly basis to bring you the most innovative updates in medicinal chemistry *Available as an online resource via ScienceDirect
Isoquinoline Alkaloids
The Isoquinoline Alkaloids presents an in-depth review of 22-sub groups of isoquinoline alkaloids all related to their common origin from the amino-acids phenylalanine and tyrosine. The coverage is not intended to be comprehensive and encyclopaedic, but all of the salient features of the elucidation of structures, structural variation, stereochemistry, chemical reactions, syntheses, biogenetic origins and relationships, and pharmacology are covered, and an extensive bibliography of original papers is provided to assist further detailed study. The opening chapter comprises a review of the formation of alkaloids from amino-acids and the general methods of structural degradation used in the definitive elucidations of structures. Two final chapters cover napthylisoquinolines, which are biogenetically distinct from those discussed in earlier chapters, and miscellaneous natural products that are rationally included with other groups. This book should be of interest to graduates and researchers in the field of organic chemistry, natural product chemistry and biochemistry.
The Practice of Medicinal Chemistry
The Practice of Medicinal Chemistry fills a gap in the list of available medicinal chemistry literature. It is a single-volume source on the practical aspects of medicinal chemistry. Considered ""the Bible"" by medicinal chemists, the book emphasizes the methods that chemists use to conduct their research and design new drug entities. It serves as a practical handbook about the drug discovery process, from conception of the molecules to drug production. The first part of the book covers the background of the subject matter, which includes the definition and history of medicinal chemistry, the measurement of biological activities, and the main phases of drug activity. The second part of the b...
Secondary Metabolites in Soil Ecology
Microbiologists and soil scientists will find this study compelling reading. It focuses on the role of bacterial, fungal and plant secondary metabolites in soil ecosystems. Our understanding of the biological function of secondary metabolites is surprisingly limited, considering our knowledge of their structural diversity and pharmaceutical activity. This book reviews functional aspects of secondary metabolite production, with a focus on interactions among soil organisms.
Improving the Resolving Power of Ultraviolet to Near-Infrared Microwave Kinetic Inductance Detectors
This thesis represents a breakthrough in our understanding of the noise processes in Microwave Kinetic Inductance Detectors (MKIDs). While the detection of ultraviolet to near-infrared light is useful for a variety of applications from dark matter searches to biological imaging and astronomy, the performance of these detectors often limits the achievable science. The author’s work explains the limits on spectral resolution broadening, and uses this knowledge to more than double the world record spectral resolution for an MKID suitable for optical and near-IR astrophysics, with emphasis on developing detectors for exoplanet detection. The techniques developed have implication for phonon control in many different devices, particularly in limiting cosmic ray-induced decoherence in superconducting qubits. In addition, this thesis is highly accessible, with a thorough, pedagogical approach that will benefit generations of students in this area.
Poppy
Poppy, the third volume in the series Medicinal and Aromatic Plants - Industrial Profiles presents up-to-date information on Poppy and related species. The introduction emphasizes the importance of Poppy, giving a historical evaluation. in the chapters describing the botany and taxonomy of the genus some novel aspects are discussed, e.g., special m
Spectrum and Power Allocation in Cognitive Radio Systems
As wireless services rapidly expand, the inefficient use of limited spectrum resources poses a critical challenge. The conventional approach to spectrum allocation, based on fixed assignments, could be more effective in meeting the escalating demand for wireless devices and systems. Cognitive radio technology offers a transformative solution by reimagining the spectrum as a multidimensional space, enabling opportunistic access to underutilized bands. However, the field of cognitive radio is still in its early stages, needing more in-depth analyses and descriptions of crucial processes. Spectrum and Power Allocation in Cognitive Radio Systems addresses this pressing need by offering a comprehensive guide for academic scholars, researchers, and industry professionals. This book delves into cognitive radio technology's foundations, organization, and challenges, providing insights into dynamic spectrum access, networking protocols, hardware architecture, and emerging applications. It presents advanced topics such as spectrum sensing algorithms, cooperative spectrum sensing, and multi-user access, offering practical solutions to enhance spectrum efficiency.
Advanced Nanocatalysts for Biodiesel Production
Advanced Nanocatalysts for Biodiesel Production is a comprehensive and advanced book on practical and theoretical concepts of nanocatalysts dealing with future processing techniques towards environmental sustainability. The book critically discusses on latest emerging advanced nanocatalysts for biodiesel production aimed at reducing complexities and cost in the quest to meet future energy demands. Efforts have been made at clarifying the scope and limitations of biodiesel production in large-scale commercialization. The book discusses the size-dependent catalytic properties of nanomaterials and their working mechanisms in biodiesel production. Life cycle assessment of optimized viable feedst...
