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Understanding the functions and properties of molecules in living systems requires a detailed knowledge of their three-dimensional structures and the conformational variability that allows them to adopt multiple functional forms. Interpreting biological systems in the language of three-dimensional structures is of fundamental importance and innumerable research groups around the world are working in this area. This book is a compilation of articles describing attempts at understanding the intricacies of biological systems through the structures of and interactions between their constituent molecules.
This volume is primarily a compilation of contributed articles representing the impact and application of Ramachandran's work on conformation analysis of biopolymers, as well as recent advances in macromolecular structural biology, involving diverse experimental and computational approaches. This volume is being published to coincide with a conference on "Biomolecular Forms and Functions: A celebration of 50 years of the Ramachandran Map" being held at the Indian Institute of Science, Bangalore, in January 2013.
This text features detailed descriptions of methods of bio molecular sequence and structure analyses of interest to students and practitioners of bioinformatics both in the corporate and academic sectors.
"Design Engineering for Industry 4.0 (DE4.0) represents the 'human-cyber-physical view of the systems realization ecosystem “that is necessary to accommodate the drivers of Industry 4.0 (IoX) and provide an open ecosystem for the realization of complex systems. Seamless integration of digital threads and digital twins throughout the product design, the development and fulfillment lifecycle; the ability to accommodate diverse and rapidly changing technologies; and the mechanisms to facilitate the creation of new opportunities for the design of products, processes, services, and systems are some of the desired characteristics of DE4.0." Jiao, R., Commuri, S. Panchal, J., Milisavljevic-Syed, ...
Interplay between Metal Ions and Nucleic Acids provides in an authoritative and timely manner in 12 stimulating chapters, written by 24 internationally recognized experts from 8 nations, and supported by nearly 1500 references, about 20 tables, and 125 illustrations, many in color, a most up-to-date view on metal ion-nucleic acid interactions; the characterization of which is covered in solution and in the solid state. The volume concentrates on modern developments encompassing topics in the wide range from G-quadruplexes via DNAzymes, catalysis at the DNA scaffold, and metal-mediated base pairs to peptide nucleic acids (PNAs) being thus of relevance, e.g., for chemistry and nanotechnology but also for molecular biology and (genetic) diagnostics.
A look at the methods and algorithms used to predict protein structure A thorough knowledge of the function and structure of proteins is critical for the advancement of biology and the life sciences as well as the development of better drugs, higher-yield crops, and even synthetic bio-fuels. To that end, this reference sheds light on the methods used for protein structure prediction and reveals the key applications of modeled structures. This indispensable book covers the applications of modeled protein structures and unravels the relationship between pure sequence information and three-dimensional structure, which continues to be one of the greatest challenges in molecular biology. With thi...
The Book Covers The Fundamental Principles And Concepts In Biotechnology Which Form The Basis For The Subject And Illustrates Their Applications In Selected Areas Such As Health Care, Agriculture, Animal Systems, Bioprocess Technologies And Environmental Aspects. This Textbook Is The Outcome Of A Costed-Ibn Project On Curriculum Development In Biotechnology For Undergraduate Study. It Is Designed To Provide A Strong Base In This Emerging, Interdisciplinary Are Which Holds Great Promise For Economic Development.