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Development of cancer, a dreadful disease of mankind, is a multi-stage process involving numerous molecular alterations at both genomic and proteomic levels. Immense research for the past several decades in the field of cancer identified many such mutations and their role in carcinogenesis. Concept of 'fusion genes' seeded way back in 20th century has now grown into a new field of cancer research. However, there is a lack of knowledge among scientists about these fusion genes and their importance in cancer, which can be mainly attributed to unavailability of a comprehensive book on this topic. Therefore, this book is first of its kind and aims at giving a detailed idea on the formation of gene fusions and their importance in the development and progression of cancer; techniques to identify novel gene fusions; and therapeutics available to target various fusion proteins and their impact in cancer therapy by compiling the information from the literature available till date.
The Indian Listener (fortnightly programme journal of AIR in English) published by The Indian State Broadcasting Service,Bombay ,started on 22 December, 1935 and was the successor to the Indian Radio Times in english, which was published beginning in July 16 of 1927. From 22 August ,1937 onwards, it was published by All India Radio,New Delhi.In 1950,it was turned into a weekly journal. Later,The Indian listener became "Akashvani" in January 5, 1958. It was made a fortnightly again on July 1,1983. It used to serve the listener as a bradshaw of broadcasting ,and give listener the useful information in an interesting manner about programmes,who writes them,take part in them and produce them alo...
This book provides insights into the 3rd International Conference on Communication, Devices and Computing (ICCDC 2021), which was held in Haldia, India, on August 16–18, 2021. It covers new ideas, applications, and the experiences of research engineers, scientists, industrialists, scholars, and students from around the globe. The proceedings highlight cutting-edge research on communication, electronic devices, and computing and address diverse areas such as 5G communication, spread spectrum systems, wireless sensor networks, and signal processing for secure communication, error control coding, printed antennas, analysis of wireless networks, antenna array systems, analog and digital signal processing for communication systems, frequency selective surfaces, radar communication, and substrate integrated waveguide and microwave passive components, which are key to state-of-the-art innovations in communication technologies.
"Despite the significant advances in cancer therapy made through constant evaluation and analysis of treatment aftereffects, the disease still remains one of the foremost causes of mortality worldwide killing more than 12 million people annually. The prime reason behind the failure of conventional chemotherapeutics which are used as the chief regimen in the comprehensive treatment of cancers is the development of chemoresistance. It can be either intrinsic or acquired and is primarily mediated via different key regulators like MDR, MAPK, NF-κB, PI3K/Akt, Wnt signaling pathways etc. Thus, agents which can target these regulatory elements or pathways and in turn sensitize cancer cells to chem...
The story of doctor Ferdinand Peeters (1918-1998) and his role in the development of the pill has held Belgium in thrall for almost a decade. It is time to introduce the real father of the contraceptive pill to the rest of the world. After years of research, Belgian journalist Karl van den Broeck concluded that not the American Gregory Pincus was the inventor of the pill. His prototype had so many adverse effects that it wasn’t a viable option in the long term. It was the Belgian doctor Ferdinand Peeters who, in 1959-1960, created the first clinically applicable contraceptive pill: Anovlar. It was this pill that set the standard for all future pills to follow. Ferdinand – Nand – Peeter...
Novel Phytopharmaceutical for Management of Disorders covers recent advances surrounding phytopharmaceuticals and their potential uses in the management of several disorders as well as in cosmetic benefits. Sections cover the concepts of phytopharmaceuticals and current highlights in disease management. This book also emphasizes phytopharmaceutical drug delivery studies in vivo–in vitro study to various target organs like lungs, liver, and brain. This book provides key information for everyone interested in disease management, drug discovery, and delivery, including medicinal chemists, cosmetic experts, nutritionists, toxicologists, drug formulators, and health care professionals. Students...
This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.
This book presents selected papers from the 2021 International Conference on Electrical and Electronics Engineering (ICEEE 2020), held on January 2–3, 2021. The book focuses on the current developments in various fields of electrical and electronics engineering, such as power generation, transmission and distribution; renewable energy sources and technologies; power electronics and applications; robotics; artificial intelligence and IoT; control, automation and instrumentation; electronics devices, circuits and systems; wireless and optical communication; RF and microwaves; VLSI; and signal processing. The book is a valuable resource for academics and industry professionals alike.