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The Ottoman Administration of Iraq, 1890-1908
This is a study of the nature of Ottoman administration under Sultan Abdulhamid and the effects of this on the three provinces that were to form the modern state of Iraq. The author provides a general commentary on the late Ottoman provincial administration and a comprehensive picture of the nature of its interaction with provincial society. In drawing on sources of the Ottoman archives, bringing together and analyzing an abundance of complex documents, this book is a fascinating contribution to the field of Middle Eastern studies.
Cancer
Examines molecular biologic techniques including proteomics, genomics, targeted therapies, RNA interference, cDNA arrays, and tissue arrays. This book contains sections discussing bioinformatics and societal issues in oncology, including regulatory issues, telemedicine, and international differences in oncology.
Cancer Chemotherapy and Biotherapy
Updated to include the newest drugs and those currently in development, this Fifth Edition is a comprehensive reference on the preclinical and clinical pharmacology of anticancer agents. Organized by drug class, the book provides the latest information on all drugs and biological agents—their mechanisms of action, interactions with other agents, toxicities, side effects, and mechanisms of resistance. The authors explain the rationale for use of drugs in specific schedules and combinations and offer guidelines for dose adjustment in particular situations. This edition's introduction includes timely information on general strategies for drug usage, the science of drug discovery and development, economic and regulatory aspects of cancer drug development, and principles of pharmacokinetics. Eight new chapters have been added and more than twenty have been significantly revised. A companion website includes the fully searchable text and an image bank.
VERGİ HUKUKU - Önemli Bilgi Notları + Yargıtay Kararları
200'e yakın önemli yargıtay kararı ve vergi hukuku ile iligli bilgilendirici notlar.
Bilge Öğretmen
Cemal Öğretmen, mesleğini seven bir insan. Öğrencileriyle ilgilenmek, onların problemlerine çözüm bulmak en büyük hobisi. İnsanların hayırlısı insanlara faydalı olandır, hadisini kendisine parola edinmiş. Sevdiği işi yapmak insanı yormaz; bizi yoran işler, "angarya" kabul ettiğimiz işlerdir, diyor. Ders anlatırken ve öğrencilerin problemleriyle uğraşırken dinlendiğini hissediyor, huzur duyuyor, mutlu oluyor. Bu roman, Cemal'in maraton koşusu gibi geçen bir yılını anlatıyor. Ateist öğrencileriyle fikir savaşlarını, Cemal'in onların önce gönlünde, sonra zihninde taht kuruşunu, alkol ve uyuşturucu batağında boğulmakta olan Remzi Bey'i ve ailesinin kurtuluşunu, oğulları Taner ve Taştan'ın bataklıkta boğuluşunu, kızları Melisa'nın melekleşmesini, kâbus gibi geçen bir öğretim yılının mutlu sonla noktalanışını anlatıyor.
Ex Vivo Engineering of the Tumor Microenvironment
This volume will outline how to recreate the tumor microenvironment, to culture primary tumors without the need for developmental priming factors, and to deliver targeted therapeutics in a manner that recapitulates pharmacokinetics in vivo. Much of what may be learned from this volume will aid in understanding many aspects of the enhanced study of tumor cell biology in a physiologic context, open new avenues for drug screening and biomarker development, and accelerate the preclinical evaluation of novel personalized medicine strategies for patients in real time.
Devita, Hellman, and Rosenberg's Cancer
Based on: DeVita, Hellman, and Rosenberg's cancer / editors, Vincent T. DeVita Jr., Theodore S. Lawrence, Steven A. Rosenberg. 9th ed. c2011.
DNA Repair and Cancer
DNA repair is a rapidly advancing field in biology and these systems represent a major defense mechanism against environmental and intracellular damaging agents such as sunlight, ionizing radiation, and reactive oxygen species. With contributions from eminent researchers, this book explores the basics and current trends in this critical field. Topi
Interface between Regulation and Statistics in Drug Development
With the critical role of statistics in the design, conduct, analysis and reporting of clinical trials or observational studies intended for regulatory purposes, numerous guidelines have been issued by regulatory authorities around the world focusing on statistical issues related to drug development. However, the available literature on this important topic is sporadic, and often not readily accessible to drug developers or regulatory personnel. This book provides a systematic exposition of the interplay between the two disciplines, including emerging themes pertaining to the acceleration of the development of pharmaceutical medicines to serve patients with unmet needs. Features: Regulatory ...
