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Papers from the symposium: The Safety and Toxicity of Nicotine, held in Braselton, Georgia, on December 6, 1996. Examines the potential risks of nicotine as a therapeutic medication for diseases such as: Alzheimer's, Parkinson's, Tourette syndrome, sleep apnea, attention deficit disorder, and more.
The fact that tobacco ingestion can affect how people feel and think has been known for millennia, placing the plant among those used spiritually, honori?cally, and habitually (Corti 1931; Wilbert 1987). However, the conclusion that nicotine - counted for many of these psychopharmacological effects did not emerge until the nineteenth century (Langley 1905). This was elegantly described by Lewin in 1931 as follows: “The decisive factor in the effects of tobacco, desired or undesired, is nicotine. . . ”(Lewin 1998). The use of nicotine as a pharmacological probe to und- stand physiological functioning at the dawn of the twentieth century was a landmark in the birth of modern neuropharmacol...
This Monograph provides a comprehensive overview of tobacco cessation, from health policy to patient care. Broad in scope, this state-of-the art collection is broken down into four sections: the changing landscape of the tobacco epidemic and challenges to curb it; treatment of tobacco dependence (pharmacotherapy, behavioural support); improving the care of patients with particular conditions who smoke (asthma, COPD, TB, cardiovascular diseases, etc.); and prevention. It also deals with some of the more controversial topics such as e-cigarettes and web applications. Readers will gain an understanding of how to implement smoking cessation into their everyday practice, but will also expand their knowledge about the policy and systems changes needed for population-wide smoking cessation.
Following the well-received first edition, the Drug Abuse Handbook, Second Edition is a thorough compendium of the knowledge of the pharmacological, medical, and legal aspects of drugs. The book examines criminalistics, pathology, pharmacokinetics, neurochemistry, treatment, as well as drugs and drug testing in the workplace and in sports, and the
Tobacco use kills more people than any other addiction and we know that addiction starts in childhood and youth. We all agree that youths should not smoke, but how can this be accomplished? What prevention messages will they find compelling? What effect does tobacco advertisingâ€"more than $10 million worth every dayâ€"have on youths? Can we responsibly and effectively restrict their access to tobacco products? These questions and more are addressed in Growing Up Tobacco Free, prepared by the Institute of Medicine to help everyone understand the troubling issues surrounding youths and tobacco use. Growing Up Tobacco Free provides a readable explanation of nicotine's effects and the pro...
This report considers the biological and behavioral mechanisms that may underlie the pathogenicity of tobacco smoke. Many Surgeon General's reports have considered research findings on mechanisms in assessing the biological plausibility of associations observed in epidemiologic studies. Mechanisms of disease are important because they may provide plausibility, which is one of the guideline criteria for assessing evidence on causation. This report specifically reviews the evidence on the potential mechanisms by which smoking causes diseases and considers whether a mechanism is likely to be operative in the production of human disease by tobacco smoke. This evidence is relevant to understanding how smoking causes disease, to identifying those who may be particularly susceptible, and to assessing the potential risks of tobacco products.
This book tells the fascinating story of the relationship of tobacco products to cancer, from the first discoveries to the present day cancer pandemic and regulatory activities. Although there are already excellent books and monographs on this topic, both in the popular press and as government summaries, none relate the scientific story at the level of non-specialist graduate and medical students, researchers, or educated popular science readers. In this book, with a primary focus on the United States, the editors — Stephen S Hecht and Dorothy K Hatsukami — bring together 24 renowned experts on the subject of tobacco and cancer to summarize specific aspects of this critical topic in relatively non-technical terms while also incorporating some personal insights related to the story of the discovery process. This highly authoritative book is also expected to be an excellent teaching tool and basis for a course for graduate and medical students on this important topic.
Tobacco is ranked as one of the major public health disasters of modern times. This book pulls together the science of tobacco-related diseases with the policy of tobacco control to offer a comprehensive preventive medicine/public health approach.