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Jian-Bing Fan is a professor at Southern Medical University, China, and founder of AnchorDx. Jin Jen has a joint appointment with the Mayo Clinic and Bristol-Myers Squibb. Neeraj Salathia is employed by Bristol-Myers Squibb. All other Topic Editors declare no competing interests with regard to the Research Topic subject.
This volume provides an overview about main RNA editing mechanisms, focusing on their functions in physiological as well as pathological conditions. Chapters guide readers through state- of-the art methodologies to investigate RNA editing through wet and dry approaches. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, RNA Editing: Methods and Protocols aims to ensure successful results in the further study of this vital field.
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This volume presents methods for the analysis of genomic variability in vertebrate neurons and broadens our knowledge in the ways we understand the brain and its neurons. The chapters in this book are divided into 5 parts, and cover the following topics: principles and approaches for discovery of somatic mosaicism in the brain, aneuploidy and ploidy variation, DNA copy number variation, LINE-1 retrotransposition, and genetic and genomic mosaicism in aging and disease. In Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your laboratory. Cutting-edge and authoritative, Genomic Mosaicism in Neurons and Other Cell Types is a valuable resource for learning about the latest techniques for the analysis of genome and genetic mosaicism in vertebrate neurons.
Melatonin (N-acetyl-5-methoxytryptamine) is a widely studied biomolecule, and its function has been investigated in bacteria, mammals, birds, amphibians, reptiles, fish and plants. Melatonin research in plants the last five years has attained an exponential growth phase and the number of publications related to phytomelatonin has significantly increased in present times. All this research is directed towards establishing multifarious roles of melatonin in plants, including the promotion of seed germination and seedling growth, influencing plant development and senescence, alteration of flowering and fruiting time and grain yield, modulating circadian rhythms, improving resistance against bio...
"I am delighted to introduce this volume of Neurosurgery by Example: Key Cases and Fundamental Principles. Neurosurgical training and practice are based on managing a wide range of complex clinical cases with expert knowledge, sound judgment, and skilled technical execution. Our goal in this series is to present exemplary cases in the manner they are actually encountered in the neurosurgical clinic, hospital emergency department, and operating room. In this volume, Drs. Peter Nakaji and Michael Levitt invited a broad range of expert contributors to share their extensive wisdom and experience in all major areas of vascular neurosurgery. Each chapter contains a classic presentation of an impor...
This book adopts an experimental approach to understanding the mechanisms of evolution and the nature of evolutionary processes, with examples drawn from microbial, plant and animal systems. It incorporates insights from remarkable recent advances in theoretical modelling, and the fields of molecular genetics and environmental genomics. Adaptation is caused by selection continually winnowing the genetic variation created by mutation. In the last decade, our knowledge of how selection operates on populations in the field and in the laboratory has increased enormously, and the principal aim of this book is to provide an up-to-date account of selection as the principal agent of evolution. In th...
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India: From Midnight to the Millennium and Beyond is an eloquent argument for the importance of India to the future of the industrialized world. Shashi Tharoor shows compellingly that India stands at the intersection of the most significant questions facing the world today. If democracy leads to inefficient political infighting, should it be sacrificed in the interest of economic well-being? Does religious fundamentalism provide a way for countries in the developing world to assert their identity in the face of Western hegemony, or is there a case for pluralism and diversity amid cultural and religious traditions? Does the entry of Western consumer goods threaten a country's economic self-su...