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Principles of Neurotransmission
During the last annual meeting of the Austrian Society for Electron Microscopy it was decided to organize scientific symposia dealing with basic problems of cytology. If possible such symposia should be arranged in cooperation with other scientific societies. We intended to arrange symposia on special fields, to be presented on several aspects by excellent scientists invited. "Neural Transmission" was chosen as a central topic for this first symposium. The subject represents a most rapidly expanding field of research and is of particular interest to morphologists, physiologists, pharmacologists, biochemists and clinicians. We are indebted to all the invited speakers for contributing their interesting papers. I feel bound to thank once more the firm of Bender, a subsidiary company of Boehringer Ingelheim and of Arzneimittelforschung Ges. m. b. H. Wien, for the generous financial support which made possible to realize the symposium. The publication of this volume, representing the papers and discussions originally read at the symposium and elaborated by the authors in detail and more extensively, was only made possible by the generous cooperation of the Springer-Verlag Vienna.
Mechanisms of Synaptic Transmission
Mechanisms of Synaptic Transmission
Mechanisms of Synaptic Transmission
Synaptic transmission plays a central role in the nervous system as the mechanism that allows for chemical and electrical communication between cells and thus connects discrete elements into the functioning whole. This is a broad account of anatomical, biochemical, embryological, medical, pathological, pharmacological, and physiological studies on synaptic transmission during the hundred years beginning in 1890. During this century, the process of synaptic transmission came to be recognized not only as the most fundamental neurophysiological process, but also as a seat of pathological changes, and as the predominant site of action for drugs used to treat a wide range of psychiatric and neuro...
Extrasynaptic neurotransmission as a way of modulating multiple neuronal functions
Extrasynaptic transmission is a unifying term for a wide variety of cellular processes, in which outside of synaptic terminals transmitter substances activate extrasynaptic receptors. Whereas “synaptic transmission” immediately refers to a process occurring at nerve terminals in which the arrival of a presynaptic impulse evokes exocytosis followed by a postsynaptic response within a millisecond time scale, extrasynaptic transmission has a wide diversity of ultrastructural and therefore mechanistic associated phenomena. In comparison to synaptic, extrasynaptic exocytosis may last for seconds or even minutes, thus expanding the timing of neuronal signaling. Extrasynaptic transmission has n...
Modulation of Synaptic Transmission and Plasticity in Nervous Systems
This volume is based on a workshop "Modulation of Synaptic Transmission and Plasticity in Nervous Systems" held in n Ciocco, Castelvecchio, Pascoli, Italy, from September 8th to 13th, 1987. The purpose of the meeting was to bring together scientists working on plasticity in nervous systems on different levels. The contributions can be subgrouped into six fields of research: 1) Presynaptic Modulation of Chemical Neurotransmission 2) Postsynaptic Signal Transduction 3) Modulation of Synaptic Transmission and Plasticity in the Hippocampus 4) Modulation of Neuromuscular Transmission 5) Molecular and Cellular Analysis of Conditioning in Marine Snails 6) Analysis of Learning and Memory in Insects ...
Synaptic Transmission
Synaptic Transmission is a comprehensive guide to the topic of neurotransmission that provides an in-depth discussion on many aspects of synapse structure and function—a fundamental part of the neuroscience discipline. Chapters include boxes that describe renowned/award-winning researchers and their contributions to the field of synaptic transmission, diseases relevant to the material presented, details of experimental approaches used to study synaptic transmission, and interesting asides that expand on topics covered. This book will inspire students to appreciate how the basic cellular and molecular biology of the synapse can lead to a better understanding of nervous system function and neurological disorders. Provides a comprehensive reference on synaptic structure, physiology, function and neurotransmission Discusses many landmark experiments in the field of synaptic transmission to emphasize core principles Includes references to primary scientific literature, relevant review articles and books, many of which could be assigned as discussion material for courses focused on this topic
