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Neuroglia
Graduate students in neuroanatomy, neurochemistry, neurophysiology, and molecular neurobiology will find the book indispensable. It is also a vital companion for researchers in these fields as well as clinicians in neurology, neurosurgery, neuropathology, neuro-oncology, physiatry, and psychiatry."--BOOK JACKET.
Neuroglia in the Aging Brain
A distinguished panel of internationally recognized neuroscientists comprehensively review the involvement of and changes in glial cells both during the normal aging process and in the major disorders of old age. Topics range from the cellular and molecular changes that occur with aging-especially aging-associated activation of astrocytes and microglia and its relation to neuronal injury and repair-to neuron-glia intercommunication. The contributors show how glial signals may be modulated by hormones, growth factors, neurotransmitters, intracellular metabolism, and intercellular exchanges, as well as by aging of the blood-brain barrier.
Neuroglia in Neurodegenerative Diseases
This book provides a comprehensive overview of the role of neuroglia in neurodegenerative diseases. Neuroglia are the most abundant cells in the nervous system and consist of several distinct cell types, such as astrocytes, oligodendrocytes,and microglia. Accumulating evidence suggests that neuroglia participate in the neurodegenerative process, and as such are essential players in a variety of diseases, including Alzheimer’s, Parkinson’s, and Huntington’s. Intended for researchers and students, the book presents recent advances concerning the biology of neuroglia as well as their interaction with neurons during disease progression. In addition, to highlight the function of neuroglia in different types of neurodegenerative disease, it also discusses their mechanisms and effects on protecting or damaging neurons.
Biology of Neuroglia
Biology of Neuroglia
Neuroglia: Function and Pathology
Diverse specialised neuroglial cells guarantee the development, preservation, and health of the central nervous system, the peripheral nervous system, the enteric nervous system, and the special senses. In the central nervous system, it is the astrocytes, oligodendrocytes, and microglia that safeguard nerve cell function and integrity that controls all behaviours and encompasses the cerebral cortex of the brain which is the root of humanity. In the peripheral nervous system, Schwann cells play the leading role, together with satellite glial cells of the sensory and autonomic ganglia, ensuring correct communication between the organs and tissues with the brain and the spinal cord. In the ente...
Neurocytology
During the second half of the 20th century, the introduction of a variety of new techniques greatly expanded our knowledge of the structure of nerve and neuroglial cells and of the organization of the nervous system at the cellular level. This new information has, however, generally been scattered throughout the literature, making it difficult for investigators to gain an overall vision of the discipline. The author has marshalled these scattered data to provide a systematic overview of the field placed within a historical context. He has correlated the major new findings with the classical notions of light microscopy and has integrated them with elements of biochemistry and cell physiology....
Pathological Potential of Neuroglia
Pathophysiological states, neurological and psychiatric diseases are almost universally considered from the neurocentric point of view, with neurons being the principal cellular element of pathological process. The brain homeostasis, which lies at the fulcrum of healthy brain function, the compromise of which invariably results in dysfunction/disease, however, is entirely controlled by neuroglia. It is becoming clear that neuroglial cells are involved in various aspects of initiation, progression and resolution of neuropathology. In this book we aim to integrate the body of information that has accumulated in recent years revealing the active role of glia in such pathophysiological processes. Understanding roles of glial cells in pathology will provide new targets for medical intervention and aide the development of much needed therapeutics. This book will be particularly useful for researchers, students, physicians and psychotherapists working in the field of neurobiology, neurology and psychiatry.
Neuroglia
1. The Concept of Neuroglia: A Historical Perspective Helmut Kettenmann and Bruce R. Ransom PART I. PROPERTIES OF NEUROGLIAL CELLS Morphology and Ultrastructure of Glial Cells Astrocytes and Ependymal Glia, 2 Andreas Reichenbach and Hartwiq Wolburg 3. Structure and Function of Oligodendrocytes Arthur M. Butt 4. Schwann Cells and Myelin Rudolf Martini 5. Microglial Cells Wolfgang J. Streit Lineage 6. Lineages of Astrocytes and Oligodendrocytes James E. Goldman 7. The Schwann Cell Lineage Kristjan R. Jessen and Rhona Mirsky 8. The Role of Neurogenic Astroglial Cells in the Devel.
Neuroglia
Neuroglia is now published as part of Brain Sciences with a new section Editor-in-Chief Prof. Sergey Kasparov.
Neuroglia in Infectious Brain Diseases
In this book, we present a discussion of the immune functions of neuroglia and their interactions with common infectious diseases in the brain. While most is known about microglia and astrocytes, as are extensively reviewed here, our understanding of other glia, including oligodendrocytes and ependymal cells, continues to grow in terms of their response to infection. Our discussion focuses on the most clinically relevant and well-studied infectious diseases, including Streptococcus pneumoniae, Neisseria meningitidis, and human immunodeficiency virus (HIV), among others, in their interactions with microglia and astrocytes. These immune responses within the central nervous system are crucial for protecting us from pathogens and yet must be carefully balanced with the need to protect brain structures that are sensitive to inflammatory damage. The complex interactions between pathogens and glia, as well as glia with other cells in the central nervous system, are an area of fascinating research that continues to grow as we attempt to translate our understanding of these processes to new treatment and prevention strategies.
