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"Insulin resistance is the main factor involved in the occurrence of the metabolic syndrome and later development of type2 diabetes. Despite decades of research on hormone's target tissues and the identification of most diverse candidates, the factors resp"
This important reference, edited by Ronald Ross Watson and Betsy Dokken, collects the research needed to make the distinct connection between pre-diabetes, diabetes, and cardiovascular disease. Glucose Intake and Utilization in Pre-Diabetes and Diabetes: Implications for Cardiovascular Disease explains the mechanisms of progression from pre-diabetes to diabetes to cardiovascular disease. Since pre-diabetes and diabetes are important cardiovascular disease risk factors, and impaired glucose metabolism among cardiac patients is extremely prevalent, the importance of reviewing pre-diabetes and its involvement in CVD complications is vital as one applies food and glycemic control to slow progres...
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The present volume summarizes current research on type 2 diabetes, its etiology, pathogenesis and long-term vascular and neurological consequences, with special emphasis on molecular and biochemical mechanisms. Alterations in insulin secretion are comprehensively treated, focusing on the role of glucokinase as glucose sensor. Moreover, insulin action is analyzed with regard to both nonoxidative glucose utilization and glucose oxidation. Concerning the complications in chronic diabetes, topics covered include the effects of high glucose concentration on cellular and endothelial functions and on the glucose phosphorylation rate in non-insulin-sensitive tissues. Furthermore, the role of oxidati...
This book focuses on essential fatty acids and eicosanoids and their role in health and disease. The group of 90 invited papers from the Fourth International Congress on Essential Fatty Acids and Eicosanoids includes such topics as: gene expression of eicosanoids; eicosanoid receptors; and the role of essential fatty acids and eicosanoids in development in utero and early life, diabetes, inflammation and the immune response, alcoholism, schizophrenia, cancer, and vascular disease.
This is the first part of the proceedings of the international symposium of the same title held in La Napoule, France, June 1989 as a satellite of the International Symposium on Cerebral Blood Flow and Metabolism. Papers cover cerebrovascular endothelium and smooth muscle, morphological and trophic studies on innervation of cerebral blood vessels, adrenergic and serotonergic and peptidergic mechanisms, cholinergic mechanisms and the basal forebrain, and excitatory amino acid and purinergic mechanisms in ischemic. Annotation copyrighted by Book News, Inc., Portland, OR