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Nitrate and nitrite are potentially dangerous substances which can have a detrimental effect on the ecological balance of rivers and lakes, and can cause harm to human health. This book puts into context the magnitude and complexity of the problems caused by nitrate and nitrite, and provides advice and information on ways to combat it.
From the Introduction With regard to nitrate and nitrite, the perceived hazards are to the ecological balance in rivers and lakes, and to human health. Increased nitrate levels in river water lead to increased growth of algae and consequent decrease in the level of biologically available oxygen (BAO). In extreme forms, the algae form unsightly blooms on the water surface, and the BAO level falls below that necessary to support fish and other animal life. At this extreme, there is little dispute that efforts should be made to restore the ecological balance, and this is best achieved by reversing the increase in nitrate concentration that caused the problem. The health hazards are less clear, ...
On cover: Health protection of consumers
On cover: Health protection of consumers
Nitrite and Nitrate in Human Health and Disease delivers a comprehensive review of nitrite and nitrate biology, from basic biochemistry to the complex physiology and metabolism of these two naturally occurring molecules in the human body. Well-organized and well referenced chapters cover the rich history of nitrite and nitrate, sources of exposure, and the physiological effects when consumed through foods containing nitrite and nitrate. The chapters are written by leading experts, all of whom share their research and perspectives in order to help define the context for benefits vs. any potential risks associated with nitrite and nitrate use, either through dietary ingestion or therapeutic dosing. This diverse collection of authors includes vascular biologists, physiologists, physicians, epidemiologists, cancer biologists, registered dieticians, chemists, and public health experts from five countries in both academia and government. Nitrite and Nitrate in Human Health and Disease provides a balanced view of nitric oxide biochemistry, and nitrite and nitrate biochemistry in physiology and in the food sciences.
This volume concentrates on the latest research information on the beneficial effects of nitrates and their fate in the environment. Adopting an integrated approach it covers the agricultural, environmental and medical aspects of this emotive topic. In addition, there is an extensive description of the biochemistry of nitrates in plants, animals and humans including the positive aspects as well as the hazards.
Nitroglycerin and other organic nitrates have been used for over a century in the treatment of angina pectoris. Millions of patients, throughout the world, have placed nitroglycerin tablets under the tongue and have experienced rapid and dramatic relief from the chest pain that frequently occurs as a manifestation of disease of the coronary arteries. The empirical observation of the safe use of nitrates for tile alleviation of the symptoms of angina have led to their widespread medical acceptance. The use of organic nitrates preceded any knowledge of their mechanism of action or their ultimate metabolic fate. Thus, more simply stated, although sub lingual nitrates helped the patients, little...
This book focuses on the issue of the toxicity or innocuousness of nitrate. The nitrogen cycle, the metabolism of nitrate, the pathological and physiological levels of nitrate in body fluids, and the beneficial effects of nitrate (particularly in the areas of infectious digestive diseases, cardiovascular diseases and cancer) are discussed. Regulations concerning nitrate are examined. It is shown that, contrary to common belief, nitrate from vegetables and tap water presents no danger to human health.
This time-saving book provides extensive coverage of all important aspects of nitrates in groundwater, ranging from prevention to problem assessment to remediation. It begins by highlighting the nitrogen cycle and related health concerns, providing both background information and a unique perspective on health issues. It then analyzes subsurface pr