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Leading scientists in the field review the genomics, molecular biology and pathogenesis of these important viruses, comprehensively covering all the recent advances.
In this eBook, original and review papers on various aspects of endogenous viral elements (EVEs) are included. EVEs are integral parts of the genomes of eukaryotic organisms and are involved in various physiological and pathological processes. The focus of this eBook is on the involvement of EVEs in cancer and autoimmune diseases. Frontiers in Microbiology 3 February 2019 | EVEs, Autoimmunity and Cancer In particular, research on endogenous retroviruses and endogenous bornaviruses is included. The presented data demonstrate that EVEs are fascinating objects that are still worth exploring.
Developments in telepathology are progressing at a great speed. As a consequence, there is a need for a broad overview of the field. This first ever book on telepathology is presented in such a way that it should make it accessible to anyone, independent of their kno- edge of technology. The text is designed to be used by all prof- sionals, including pathologists, surgeons, nurses and allied health professionals, and computer scientists. In a very short time, driven by technical developments, the field of telepathology has become too extensive to be covered by only a small number of experts. Therefore, this Telepathology book has been written with chapter contributions from a host of renowned international authorities in telepathology (see the Table of Contents and the List of Contributors). This ensures that the subject matter focusing on recent advances in telepathology is truly up to date. Our guiding hope during this task was that as editors of multiple chapters we could still write with a single voice and keep the content coherent and simple. We hope that the clarity of this book makes up for any limitations in its comprehensiveness.
In this New York Times bestseller and longlist nominee for the National Book Award, “our greatest living chronicler of the natural world” (The New York Times), David Quammen explains how recent discoveries in molecular biology affect our understanding of evolution and life’s history. In the mid-1970s, scientists began using DNA sequences to reexamine the history of all life. Perhaps the most startling discovery to come out of this new field—the study of life’s diversity and relatedness at the molecular level—is horizontal gene transfer (HGT), or the movement of genes across species lines. It turns out that HGT has been widespread and important; we now know that roughly eight perc...
The volume covers the preparation and analysis of model systems for biological electron microscopy. The volume has chapters about prokaryotic as well as eukaryotic systems that are used as so-called model organisms in modern cell biology. These systems include the most popular systems, such as budding and fission yeast, the roundworm C. elegans, the fly Drosophila, zebrafish, mouse, and Arabidopsis, but also organisms that are less frequently used in cell biology, such as Chlamydomonas, Dictyostelium, Trypanosoma, faltworms, Axolotl and others. In addition, tissues and tissue culture systems are also covered. These systems are used for very diverse areas of cell biology, such as cell divisio...
Proteins are the work horses of the cell. As regulators of protein function, protein kinases are involved in the control of cellular functions via intricate signalling pathways, allowing for fine tuning of physiological functions. This book is a collaborative effort, with contribution from experts in their respective fields, reflecting the spirit of collaboration - across disciplines and borders - that exists in modern science. Here, we review the existing literature and, on occasions, provide novel data on the function of protein kinases in various systems. We also discuss the implications of these findings in the context of disease, treatment, and drug development.