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From Systems Biology to Systems Medicine
Throughout most of the twentieth century, the biomedical model dominated healthcare. However, the biomedical model had its critics, who proposed alternative models to replace it. Eventually, biomedicine became fragmented at its foundations with a variety of approaches to its nature and practice. Medicine's current response to this fragmentation is to combine these disparate approaches into a single system--systems medicine. In the present book, I examine the shift, during the postgenomics era, from the biomedical model to systems medicine vis-à-vis systems biology, as well as the challenges facing systems medicine's implementation in the twenty-first century. The main goal of the present bo...
Chronic Lymphocytic Leukemia
Chronic Lymphocytic Leukemia (CLL) is the most common leukemia in the western world, seen mostly in the elderly age-group and has a very variable clinical outcome. Traditionally considered an indolent, antigen inexperienced leukemia of slowly accumulating cells that do not die, researchers now acknowledge that CLL cells are highly proliferative, antigen experienced cells that have a high cell turnover and a subset show an aggressive clinical course. The onset of the disease is usually asymptomatic; only abnormalities in whole blood count such as leukocytosis with lymphocytosis are found. Nowadays, CLL is diagnosed more often at an early, asymptomatic stage due to more frequent routine blood tests. More advanced stages are characterized by lymphadenopathy, hepatomegaly/splenomegaly, recurrent infections, weakness, pallor and hemorrhagic diathesis, and general symptoms such as weight loss, fever and night sweats are observed. This book reviews the diagnosis, treatment options and prognosis of CLL.
Critical Care Procedure Book
This book provides a comprehensive review, with illustrations and guidelines, of bed side procedures performed in critical care units. Critical care procedures are included in a step by step manner. They are easy to review and help perform procedures confidently at the bed side with minimal complications. It is a great review book of procedures for the board exams, and gives an excellent review of intensive care unit procedures for clinicians and trainees. This book includes neuro-critical care, cardiothoracic and medical surgical intensive care unit procedures.
Human Body Size and the Laws of Scaling
Several books have been published on scaling in biology and its ramifications in the animal kingdom. However, none has specifically examined the multifaceted effects of how changes in human height create disproportionately larger changes in weight, surface area, strength and other physiological parameters. Yet, the impact of these non-linear effects on individual humans as well as our world's environment is enormous. Since increasing human body size has widespread ramifications, this book presents findings on the human species and its ecological niche. its community and how the species interacts with its environment. Thus, a few chapters provide an ecological overview of how increasing human body size relates to human evolution, fitness, health, survival and the environment. This book provides a unique purview of the laws of scaling on human performance, health, longevity and the environment. Numerous examples from various research disciplines are used to illustrate the impact of increasing body size on many aspects of human enterprises, including work output, athletics and intellectual performance.
Dry Powder Inhalers
This book is a compilation of most works published during 2000-2016 in the area of dry powder inhalers, especially related to the issues with formulation and device design. The dry powder inhalers aim to deliver the medication to the respiratory airways. It is suitable for postgraduate students and researchers who work in the areas of dry powder inhalers. It provides some background knowledge in size characterization, flow properties, forces, and interaction of air and particles. It also ends with in vitro quality control of dry powder inhalers. This book was finished in Hawaii where the author spent his time during April 2016. Thank you to Prince of Songkla University for the financial supp...
Forest Medicine
Imagine a new medical science that could let you know how to be more active, more relaxed and healthier with reduced stress and reduced risk of lifestyle-related disease and cancer by visiting forests. This new medical science is called forest medicine. Forest medicine encompasses the effects of forest environments on human health and is a new interdisciplinary science, belonging to the categories of alternative medicine, environmental medicine and preventive medicine. This book presents up-to-date findings in forest medicine to show the beneficial effects of forest environments on human health. (Imprint: Novinka)
Knee Osteoarthritis
Osteoarthritis, the most common joint disease, causes appreciable disability in a high percentage of older adults. Commonly attributed to progressive disruption of the articular cartilage and underlying bone structures constituting the joint, the condition can be extremely debilitating due to its widespread aversive consequences. Knee osteoarthritis (OA) is the most frequent localization of the arthrosis disease and the most common arthropathy of the knee, affecting over 37% of the population aged over 60 years and representing the main cause of pain and disability. In this book, Chapter One describes the most common less well documented psychological complications that can prevail in knee osteoarthritis, their implications, and possible solutions for reducing the extent and severity of this disabling condition. Chapter Two reviews biological pathways in knee osteoarthritis. Chapter Three discusses ozone therapy for management of OA.
Psychology of Stress
Stress is a physical response to an undesirable situation. It can be short-term (acute) or long-term (chronic). This book deals with the dazzling complexity of this good-bad phenomenon and presents up-to-date research from throughout the world.
Skin Anatomy and Physiology Research Developments
Skin anatomy refers to the structure of the skin, which consists of two principal parts: the outer, thinner portion which is called the epidermis and the inner, thicker portion which is known as the dermis. Alternatively, skin physiology is the subdivision of physiology which concerns the functions of the skin including the regulation of body temperature, protection, sensation, excretion, immunity, blood reservoir and the synthesis of Vitamin D. There are more than a thousand conditions that may affect the skin but some of the most common skin diseases include rashes, bacterial infections, fungal infections, parasitic infections, pigmentation disorders, tumours and cancers and skin diseases that result from trauma. This book gathers the latest research from around the globe in this field.
Ryan's Retina E-Book
Through six outstanding and award-winning editions, Ryan's Retina has offered unsurpassed coverage of this complex subspecialty—everything from basic science through the latest research, therapeutics, technology, and surgical techniques. The fully revised 7th Edition, edited by Drs. SriniVas R. Sadda, Andrew P. Schachat, Charles P. Wilkinson, David R. Hinton, Peter Wiedemann, K. Bailey Freund, and David Sarraf, continues the tradition of excellence, balancing the latest scientific research and clinical correlations and covering everything you need to know on retinal diagnosis, treatment, development, structure, function, and pathophysiology. More than 300 global contributors share their kn...
