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Michelin
Please note that the content of this book primarily consists of articles available from Wikipedia or other free sources online. Pages: 150. Chapters: Bibendum, Michelin Challenge Bibendum, O'Galop, Thervoy Kandigai, Tweel.
Immuno-Oncology
Over the last decade, immuno-oncology has witnessed an astonishing pace of discovery and innovation translating into unprecedented successes in the clinical setting, arguably representing one of the most profound and transforming revolution in the history of cancer therapy. This book provides a concise and accurate outline of the main developments in major tumor types including melanoma, lung, breast, brain and renal cell cancers. In addition, transversal chapters that describe the commonalities of some of the therapeutic strategies are provided to cover topics like immune checkpoint biology, T cell engineering or rational combination therapies. Each chapter has been authored by senior key o...
Catalysis
"Catalysis" is sure to be of interest to readers working in academia and industry that need an up-to-date critical analysis and summary of catalysis research and applications.
Behavior and Cognitive Therapy Today
This book carries the Proceedings of the European Association for Behavioural and Cognitive Therapy conference held in Venice in September 1997 and is dedicated to the memory of Hans Eysenck. The EACBT conference provides a rare opportunity for a wide range of clinicians and researchers from all over Europe and the USSR to come together, resulting in a highly topical and valuable range of scientific presentations. The Proceedings comprises over twenty papers addressing key subjects in terms of behavioural and cognitive therapy including panic, affective disorders, paraphilia, schizophrenia, PTSD, obsession and other psychological disorders. Of particular interest are chapters on the use of cognitive behaviour therapy versus supportive therapy in social phobia (Cottraux), the psychological treatment of paraphilias (De Silva), the theory and treatment of PTSD (Foa), the use of Diagnostic Profiling System in treatment planning (Freeman) and a cognitive theory of obsession (Rachman).
DNA Photodamage
Written in an accessible and comprehensive manner, DNA Photodamage will appeal to all scientists working in the area whether specialists in the discipline or not and provides a complete coverage of the field, from ultrafast spectroscopy to biomedical research.
Computational Methods in Drug Discovery and Repurposing for Cancer Therapy
Computational Methods in Drug Discovery and Repurposing for Cancer Therapy provides knowledge about ongoing research as well as computational approaches for drug discovery and repurposing for cancer therapy. The book also provides detailed descriptions about target molecules, pathways, and their inhibitors for easy understanding and applicability. The book discusses tools and techniques such as integrated bioinformatics approaches, systems biology tools, molecular docking, computational chemistry, artificial intelligence, machine learning, structure-based virtual screening, biomarkers, and transcriptome; those are discussed in the context of different cancer types, such as colon, pancreatic,...
Computational and Experimental Studies in Alzheimer's Disease
This reference book compiles the recent advances in computational and experimental modelling to screen and manage Alzheimer’s disease. It covers basic etiopathology and various in vitro and in vivo strategies of disease intervention. The book discusses how computer-aided drug design approaches reduce costs and increase biological test efficiency. It reviews the screening for anti-Alzheimer drugs and biomarker analysis of disease inhibitors. The book also explores mechanistic aspects of neurodegeneration and the use of natural products as therapeutics for Alzheimer’s disease. Key features: Elaborates on the computational modelling of protein target inhibitors as anti-Alzheimer’s agents Explains the role of phytomolecules and natural products in Alzheimer’s therapy Reviews preclinical ways to assess drugs focusing on Alzheimer’s disease Covers biomarker analysis for Alzheimer’s disease Discusses the onset and progression of Alzheimer’s disease The book is meant for professionals, researchers, and students of neuroscience, psychology, and computational neurosciences.
The Handbook of Medicinal Chemistry: Principles and Practice
The 2nd edition of The Handbook of Medicinal Chemistry is a carefully curated compilation of writing from global experts. Using their broad experience of medicinal chemistry, project leadership and drug discovery from both industry, academic and charity perspectives they are able to provide unparalleled insight into the field in a single, invaluable volume.
Toxicity: 77 Must-Know Predictions of Organic Compounds
Due to the advances of various methods for the prediction of toxicity of organic compounds and ionic liquids (ILs), it is necessary to review these methods for scientists and students. It is essential to compare the advantages and shortcomings of these methods. Since many organic compounds and ILs are synthesized each year, this book introduces suitable models for the assessment of their toxicities. This book reviews the best predictive methods for the prediction of toxicity of organic compounds and ILs, which were derived by in vitro or in vivo experiments. Different available quantitative structure‐toxicity relationship (QSTR) models based on various descriptors have been discussed to pr...
Profiles of Drug Substances, Excipients, and Related Methodology
Profiles of Drug Substances, Excipients, and Related Methodology, Volume 49 provides timely and pertinent information on a variety of timely topics, including Physical Profiles of Drug Substances and Excipients; Analytical Profiles of Drug Substances and Excipients; ADME Profiles of Drug Substances and Excipients; Methodology Related to the Characterization of Drug Substances and Excipients; and Methods of Chemical Synthesis. In addition, it includes comprehensive profiles of five drug compounds: Deferasirox, Duvelisib, Regorafenib, Ponatinib and Avanafil. Finally, the book contains a chapter on Regulation and Standardization of Herbal Drugs: Current status, Limitation, Challenge’s, and Future Prospectives. Offers a comprehensive review of the biological, chemical, and physical characteristics of commonly prescribed medications Provides synthesis and pathways of physical or biological degradation of selected drug substances Presents the pharmacology of certain drug substances Describes nearly all analytical methods used to identify and quantify drug substances
