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Protein Interactions
A fundamental guide to the burgeoning field of protein interactions From enzymes to transcription factors to cell membrane receptors, proteins are at the heart of biological cell function. Virtually all cellular processes are governed by their interactions, with one another, with cell bodies, with DNA, or with small molecules. The systematic study of these interactions is called Interactomics, and research within this new field promises to shape the future of molecular cell biology. Protein Interactions goes beyond any existing guide to protein interactions, presenting the first truly comprehensive overview of the field. Edited by two leading scholars in the field of protein bioinformatics, ...
Challenges of the Modern Economy
The book focuses on a systemic study of the challenges of the modern economy and related problems and areas of sustainable development of countries, regions, and businesses, with particular attention paid to the new prospects offered by the spread of digital technology. The book’s contribution to the literature is that it reveals the specifics and digital perspectives of supporting the SDGs in the economy at every level of the economy: country, regional, and corporate, considering sectoral specificities—this is reflected in six parts of the book. Part 1 identifies contemporary challenges of the modern economy as barriers to sustainable development. Part 2 reflects the future direction of...
Algorithms and Methods in Structural Bioinformatics
The three-dimensional structure and function of molecules present many challenges and opportunities for developing an understanding of biological systems. With the increasing availability of molecular structures and the advancing accuracy of structure predictions and molecular simulations, the space for algorithmic advancement on many analytical and predictive problems is both broad and deep. To support this field, a rich set of methods and algorithms are available, addressing a variety of important problems such as protein-protein interactions, the effect of mutations on protein structure and function, and protein structure determination. Despite recent advancements in the field, in particular in protein folding with the development of AlphaFold, many problems still remain unsolved. In this book we focus on a number of topics in Structural Bioinformatics: Cryo-EM structural detection, protein conformational exploration, elucidation of molecular binding surface using geometry, the effect of mutations, insertions and deletions on protein structural stability, and protein-ligand binding.
Science
Vols. for 1911-13 contain the Proceedings of the Helminothological Society of Washington, ISSN 0018-0120, 1st-15th meeting.
Going Global through Social Sciences and Humanities: A Systems and ICT Perspective
This book presents contributions submitted to the 2nd international conference Going Global through Social Sciences and Humanities (GGSSH 2019) held in Tomsk, Russia on 27–28 February 2019. The conference focused on such issues as interdisciplinary pedagogy, language teaching and learning, cultural studies and linguistics, particularly highlighting global academic integration and professional development for research. As such, the event provided a platform for discussions and sharing publication activities, to help Russian academics to take first steps toward global research. Showcasing the ongoing Russian research in focus areas, this book is of interest to a diverse academic audience working in social sciences and humanities, particularly those from the post-Soviet countries.
Social Mobility, Social Inequality, and the Role of Higher Education
The book explores the role of higher education in increasing social mobility and reducing social inequality in today’s world. The first part examines the cultural openness of the knowledge society and its contribution to reducing social inequalities. The second part examines inclusive higher education in support of social mobility. The third part reveals digital technologies in higher education and their significance for the growth of social mobility. The fourth part discusses the best international practices and offers recommendations for educational management in support of reducing social inequalities.
Antarctic Peninsula Region of the Southern Ocean
The book is based on results from the Russian expedition in the region of the Antarctic Peninsula and Powell Basin in the northern part of the Weddell Sea, as well as on the review of earlier research in the region. The main goal of the research was to collect the newest data and study the physical properties and ecology of this key region of the Southern Ocean. Data analysis is supplemented with numerical modeling of the atmosphere-ocean interaction and circulation in the adjacent region, including research on rogue waves. The focus of the study was the Antarctic Circumpolar Current, currents and water properties in the Bransfield Strait and Antarctic Sound, properties of seawater, currents, ecosystem and biological communities in the Powell Basin of the northwestern Weddell Sea, and their variations. An attempt is made to reveal the role of various components of the Antarctic environment in the formation of biological productivity and maintenance of the Antarctic krill population. This is especially important as in the last decades the Antarctic environment has experienced significant changes related to the global climatic trends.
