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Il giardino delle erbe
OGNI COPPIA HA I SUOI SEGRETI CHE GLI ALTRI NON POSSONO CAPIRE Tra i panorami mozzafiato della riviera ligure, in una grande cascina ristrutturata trasformata in borgo, Linda Bonsanti vive insieme a suo marito Fabio e alla piccola Adele. Accanto a loro abitano i genitori di lei, e poco più in là Greta, l’amica inseparabile di Linda. Protette dalle piante aromatiche del Giardino delle Erbe, da generazioni le donne del borgo si scambiano confidenze, ridono, sognano, piangono insieme. Un’ombra di indicibile sospetto grava sul cuore di Linda. Da qualche tempo Fabio è strano, non la racconta giusta: e se avesse un’altra? Greta sa qualcosa ma non trova le parole per dirglielo: come si ges...
Middle School: Escape to Australia
Rafe Khatchadorian is getting the Hollywood treatment in a film version of Middle School: The Worst Years of My Life starring Griffin Gluck, Lauren Graham, Rob Riggle and Thomas Barbusca. Rafe isn't exactly considered a winner in Hills Village Middle School to say the least, but everything's about to change: he's won a school-wide art competition, and the fabulous prize is getting to jet-set off to Australia for a whirlwind adventure! But Rafe soon finds that living in the Land Down Under is harder than he could've ever imagined; his host-siblings are anything but welcoming, the burning temperatures are torturous, and poisonous critters are ready to sting or eat him at every step. So with the help of some new misfit friends, Rafe sets out to show everyone what he does best: create utter mayhem! Previously published as Middle School: Rafe's Aussie Adventure
Tutto ciò che la luce tocca
«Un romanzo come nessun altro». Amitav Ghosh Shai è una giovane donna indiana disillusa e stanca, ma decisa a ritrovarsi. Un viaggio per salutare la sua vecchia tata le farà scoprire radici indigene che le parlano di futuro più di quanto non facesse la grande città. Evelyn è una studentessa dell’Inghilterra edoardiana che osa interessarsi di botanica e salpare alla volta dell’India non per cercare un marito, ma una pianta da studiare. E poi c’è Goethe, lo scrittore, che durante il suo viaggio in Italia trova un’ispirazione decisiva e illuminante. Tre storie, tre epoche, tre luoghi diversi. Tre personaggi che, a un certo punto della loro vita, si ritrovano a cercare una pianta...
Godspeed
'Mesmerising.' The Herald, Best Books to read this summer'A glorious novel, as lyrical as it is suspenseful - breathless, tense, and shimmering.' STEPH CHA'My daddy always told me, if it looks too good to be true - then it probably is.'Bart, Teddy and Cole have been best friends since childhood. Having founded their own small-town construction company, they yearn to build a legacy, something to leave behind to their families. So when Gretchen Connors, a mysterious millionaire lawyer from California, approaches them with a stunning, almost formidable project in the mountains above their town, the three friends convince themselves it's the job which will secure their future.But what is Gretchen hiding from them? And why does the build have to be complete by Christmas, a near-impossible deadline? With the lines between ambition and greed more slippery and dangerous than the three friends ever imagined, how far will they push themselves and what will be the cost of their dream?From the author of the international bestseller Shotgun Lovesongs, Godspeed is an unforgettable tale of family, friendship and temptation.
Alto
Everyone is familiar with the words diva or prima donna, which have come to mean a (usually) outrageous operatic soprano, but there was a time when the star of the show was more often a contralto, or a soprano singing in today's mezzo-soprano range. This performer was referred to as an alto. In the 17th and 18th centuries, the male and female leading roles were likely to be sung by emasculated males, the alto castrati, although there were many great female altos during this period as well. The music for these fantastic artists, written by such composers as Porpora, Vinci, Hasse, and even Handel, has been largely forgotten. At the beginning of the 19th century, as the castrati died out, their...
China Dolls
It's 1938 and the exclusive Oriental nightclub in San Francisco's Forbidden City is holding auditions for showgirls. In the dark, scandalous glamour of the club, three girls from very different backgrounds stumble into each other lives. All the girls have secrets. Grace, an American-born Chinese girl, has fled the Midwest and an abusive father. Helen is from a Chinese family which has deep roots in San Francisco's Chinatown. And, as both her friends know, Ruby is Japanese passing as Chinese. Then, in a heartbeat, everything changes. The Japanese attack Pearl Harbor and paranoia, suspicion, and a shocking act of betrayal, threaten to destroy their lives.
Human Tumor-Derived p53 Mutants: A Growing Family of Oncoproteins
TP53 gene mutations are present in more than half of all human cancers. The resulting proteins are mostly full-length with a single amino acid change and are abundantly expressed in cancer cells. Some of the mutant p53 proteins gain oncogenic functions (GOF) through which it actively contribute to the aberrant cell proliferation, increased resistance to apoptotic stimuli and ability to metastasize. Gain of function mutant p53 proteins can transcriptionally regulate the expression of a large plethora of target genes. This mainly occurs through the formation of oncogenic transcriptional competent complexes that include mutant p53 protein, known transcription factors, posttranslational modifier...
The Women in Black
“The book I most often give as a gift to cheer people up.” —Hilary Mantel “Tart, beguiling, witty and compassionate, Madeleine St. John’s novel is a literary boost for the spirits.” —Maureen Corrigan, Fresh Air “A deceptively smart comic gem.” –The New York Times Book Review “Witty and delicious.” –People The women in black, so named for the black frocks they wear while working at Goode’s department store, are busy selling ladies’ dresses during the holiday rush. But they somehow find time to pursue other goals… Patty, in her mid-thirties, has been working at Goode’s for years. Her husband, Frank, eats a steak for dinner every night, watches a few minutes of...
Massimo Puppieno
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