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A guide to endocrinology with surgical aspects
The textbook "A guide to endocrinology with surgical aspects" has been written according to the educational qualification characteristics and educational programs of professional training, as well as the principles of the European Credit Transfer System. The textbook is designed for English-speaking students of Higher Medical Educational Establishments of the III and IV levels of accreditation. Though intended for medical students, this handbook will also be of use for general practitioners and medical specialists who speak English.
Clinical pharmacology for physicians and surgeons
The textbook "Clinical pharmacology for physicians and surgeons" has been written according to the characteristics of educational qualifications and professional training programs, as well as according to the principles of the Credit Transfer System.
Pharmacological aspects in general medicine and surgery for dental students
The textbook "Pharmacological aspects in general medicine and surgery for dental students" has been written according to the educational qualification characteristics and educational programs of professional training, as well as according to the principles of the Credit Transfer System. For English speaking students of High Medical Institutions of IV accreditation level. Thus, while intended primary for medical students, we believe this handbook will also be of use for general practitioners and medical specialists who know English.
Topical issues of science and practice
Abstracts of VII International Scientific and Practical Conference
Prognosis in Advanced Cancer
In order to make decisions and offer quality health care, it is essential to be able to predict survival and other outcomes. This practical, evidence-based book brings together prognosis information for patients with advanced cancer.
Brain Metastases from Primary Tumors Volume 1
With an annual rate of more than 12 million global diagnoses and 7.6 million deaths, the societal and economic burden of cancer cannot be overstated. Brain metastases are the most common malignant tumors of the central nervous system, yet their incidence appears to be increasing in spite of the advancement of cancer therapies. While much is known about primary cancers (including primary brain tumors), less work has been done to uncover the roots of metastatic disease. Brain Metastases from Primary Tumors Volume 1 fills that gap, serving as the first reference to focus primarily on the link between primary cancers and brain metastases. This link is explored for the most common cancer types ...
Insulin Resistance and Cancer
This book reviews the epidemiological associations between insulin resistance and cancer. This is followed by reviews of animal models which support this relationship and provide insight into potential mechanisms. Several chapters then provide detailed examination of the cellular and molecular changes characterizing the insulin resistant state, such as hyperinsulinemia, abnormal metabolism and hormone signaling, and how these interact with various tumor characteristics. For example some tumors present increased quantities of the fetal form of the insulin receptor, unique regulation of oxidative (Krebs’ cycle) metabolism (Warburg effect), as well as mutations in various relevant signaling pathways. Finally, the clinical implications of these data are integrated with considerations of insulin “sensitization” and potential metabolic interventions to prevent and treat cancer. It should be noted that while a number of cancers are associated with obesity the authors here have focused primarily on breast cancer as a key and significant model.
