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Peptides and Neurological Disease
Peptides and Neurological Disease
The Basal Ganglia V
This volume, The Basal Ganglia V, is derived from proceedings of the fifth Triennial Meeting of the International Basal Ganglia Society (IBAGS). The Meeting was held from 23-26 May, 1995, at Nemuno-Sato, in the Mie Prefecture of central Japan, not far from the traditional birth place of the country. As at previous Meetings, our aim was to hear and discuss new ideas and data on the Basal Ganglia. About one hundred papers were presented, on platform or as posters. We had valuable talks, stimulating discussions, and agreeable social contacts. Although just before this Meeting, there were several unusual accidents in Japan, a big earthquake in the Kobe area, not far from the Meeting place, and t...
Annual Reports in Medicinal Chemistry
Annual Reports in Medicinal Chemistry
Chemical Signalling in the Basal Ganglia
Discusses themes of current interest in the basal ganglia. The work provides tools with which to tackle the remaining questions and experimentation on basal ganglia systems.
Advances in Neural Science
Part of a series which aims to cover recent knowledge in the field of neural science, this volume discusses such topics as: the molecular bases of nerve regeneration; plasticity of descending spinal pathways in developing mammals; and development of the mammalian auditory hindbrain.
Substance P in the Nervous system
The Novartis Foundation Series is a popular collection of the proceedings from Novartis Foundation Symposia, in which groups of leading scientists from a range of topics across biology, chemistry and medicine assembled to present papers and discuss results. The Novartis Foundation, originally known as the Ciba Foundation, is well known to scientists and clinicians around the world.
Clinical Aspects of Sensory Motor Integration
The ability to use tools skillfully is generally regarded as one of the major achievements in the evolutionary development of the human nervous system. It is possible for controlled movements of muscles to be executed only if sensory information is integrated into complex neural circuits at various hierarchical levels. The chapters in this volume deal with basic and clinical aspects of integrative processing of sensory and motor activities. New findings emphasize the important influence of somatosensory activity such as tactile, proprioceptive, noxious cutaneous, and articular input on motor output. Furthermore, recordings of evoked potentials as well as unit recordings indicate that sensory...
Peptide Receptors, Part II
Peptide Receptors Part I was published in 2000 (as volume 16 of the Handbook of Chemical Neuroanatomy series). This volume summarized current knowledge on the discrete anatomical distribution of ten families of neuropeptide receptors expressed in the mammalian CNS. Part II is its natural complement with chapters covering six additional families of neuropeptide receptors for ligands ranging from well known peptides such as the opioids and neurotensin to recently isolated ones like the orexins. As in the case of Part I, this volume integrates photomontages and maps of quantitative receptor autoradiography, in situ hybridization histochemistry and immunocytochemistry. Data derived from transgenic and knock-out animals are also summarized, helping to decipher the possible physiological and Pathophysiological role(s) of a given peptide family. Some chapters also review current knowledge on the profile of internalization of the neuropeptide-receptor complex, an area of intense research activities that should help to better understand mechanisms involved in desensitization and tachyphylaxis.
