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Cellular Effects of Heavy Metals
The term “heavy metals” is used as a group name of toxic metals and metalloids (semimetals) causing contaminations and ecotoxicity. In strict chemical sense the density of heavy metals is higher than 5 g/cm3. From biological point of view as microelements they can be divided into two major groups. a. For their physiological function organisms and cells require essential microelements such as iron, chromium (III), cobalt, copper, manganese, molidenium, zinc. b. The other group of heavy metals is toxic to the health or environment. Of highest concern are the emissions of As, Cd, Co, Cu, Hg, Mn, Ni, Pb, Sn, Tl. The toxicity of heavy metals is well known at organizational level, while less a...
Crime and Crime Reduction
The problems associated with groups that commit crime are well known and notoriously complex. However, there are many questions that we still cannot answer with certainty. This book seeks to deepen understanding of the group processes involved in crime and the treatment of offenders’ thoughts and behaviour. Together, the chapters in this volume address the following questions: Are people more likely to commit crime because of the influence of their group? Does group membership cause people to become criminals, or does the group merely foster people’s pre-existing criminal inclinations? How does group membership exert such a strong hold on people so that some risk imprisonment or even dea...
Chemistry and Biology of Serpins
Proceedings of an International Symposium held in Chapel Hill, North Carolina, April 13-16, 1996
Poverty Amidst Prosperity
Demonstrates how people reacted to poverty and highlights their coping strategies
Metalloenzymes
Metalloenzymes: From Bench to Bedside offers a thorough overview of metalloenzymes, spanning biochemical and structural features, pharmacology, and biotechnological applications. After a brief overview, international experts in the field discuss a wide range of magnesium, calcium, zinc, manganese, nickel, iron, copper, cadmium, molybdenum, and tungsten enzymes, along with catalytic roles within their active sites. With a uniform approach throughout, each chapter includes the structure and function of the enzyme, physiologic and pathologic roles, inhibitors and activators of the enzyme (and their design), and clinical agents or compounds applied in medicine and drug discovery. This book enables scientists across academia and industry to adopt ongoing metalloenzyme research, and continuous discovery of novel metalloenzymes, in new life science studies and clinical applications. - Examines a range of metalloenzymes, from biochemistry to pharmacology and drug design - Each chapter examines enzyme structure and function, physiologic and pathologic roles, inhibitors and activators, and clinical application - Features chapter contributions from international experts in the field
