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Current Topics in Cellular Regulation, Volume 18: Biological Cycles covers topics on the events of molecular biology, cellular communication, and the merging of cell structure to biochemical function. The book discusses the ornithin-urea cycle; the cycles of glutathione metabolism and transport; and the role of multienzymatic proteins in mammalian pyrimidine biosynthesis. The text also describes the significance of interconvertible enzyme cycles in cellular regulation; regulation of mammalian pyruvate dehydrogenase complex by a phosphorylation-dephosphorylation cycle; replenishment of citric acid cycle intermediates by the purine nucleotide cycle in rat skeletal muscle. The control of a secondary pathway of ethanol metabolism by differences in redox state; the role of aldolase and fructose bisphosphatase in the control of gluconeogenesis and glycolysis; and the fructose 6-phosphate/fructose 1,6-bisphosphate cycle are also considered. The book further tackles the cycles in polysaccharide biosynthesis and other important biological cycles. Biologists, microbiologists, cellular biologists, and biochemists will find the book invaluable.
The three-volume set LNCS 10277-10279 constitutes the refereed proceedings of the11th International Conference on Universal Access in Human-Computer Interaction, UAHCI 2017, held as part of the 19th International Conference on Human-Computer Interaction, HCII 2017, in Vancouver, BC, Canada in July 2017, jointly with 14 other thematically similar conferences. The total of 1228 papers presented at the HCII 2017 conferences were carefully reviewed and selected from 4340 submissions. The papers included in the three UAHCI 2017 volumes address the following major topics: Design for All Methods and Practice; Accessibility and Usability Guidelines and Evaluation; User and Context Modelling and Monitoring and Interaction Adaptation; Design for Children; Sign Language Processing; Universal Access to Virtual and Augmented Reality; Non Visual and Tactile Interaction; Gesture and Gaze-Based Interaction; Universal Access to Health and Rehabilitation; Universal Access to Education and Learning; Universal Access to Mobility; Universal Access to Information and Media; and Design for Quality of Life Technologies.
The four-volume set LNCS 8513-8516 constitutes the refereed proceedings of the 8th International Conference on Universal Access in Human-Computer Interaction, UAHCI 2014, held as part of the 16th International Conference on Human-Computer Interaction, HCII 2014, held in Heraklion, Crete, Greece in June 2014, jointly with 14 other thematically similar conferences. The total of 1476 papers and 220 posters presented at the HCII 2014 conferences was carefully reviewed and selected from 4766 submissions. These papers address the latest research and development efforts and highlight the human aspects of design and use of computing systems. The papers thoroughly cover the entire field of human-comp...
The success rate for treatment of primary neoplasms has improved sig nificantly due to improved surgical, radiotherapy, and chemotherapy methods, and by supportive patient care. In contrast, the treatment of cancer metastases, the cause of most cancer deaths, has not been very successful. Approximately 50% or more of patients with primary malignant neoplasms already have established metastases. Consequently, the most important problem in cancer treatment is the destruction or prevention of metastases. Metastases research has obvious clinical importance. Yet it has only been recently that investigators have attempted to study the mechanisms in volved in this process. This is in part due to th...
Environmental Epidemiology: Exposure and Disease is a unique resource identifying priorities for public health research in selected areas of environmental epidemiology. Drawn from the proceedings of an international workshop on this topic, the book is a compilation of the specialized knowledge and opinions of environmental epidemiology experts. Organized by the Rome division of the World Health Organization (WHO) European Centre for Environment and Health, the goal of the 1993 workshop, Setting Priorities in Environmental Epidemiology, was to establish a consensus among the experts in the selected areas. The chapters in Environmental Epidemiology: Exposure and Disease cover environmental epi...
This book is the latest volume in a highly successful series within Comprehensive Biochemistry and provides a historical and autobiographical perspective of the development of the field through the contributions of leading individuals who reflect on their careers and their impact on biochemistry. The book is essential reading for everybody, from graduate student to professor, placing in context major advances not only in biochemical terms but in relation to historical and social developments. Readers will be delighted by the lively style and the insight into the lives and careers of leading scientists of their time.
Environmental Medicine, Second Edition stresses the importance of the medicine of the environment and emphasizes the advantages which must emanate from a multidisciplinary approach to the method in which environmental factors impinge on the health and wellbeing of the human race. The selection first offers information on the environment, its influences, and hazards to health and trace element concentrations in various environments. Discussions focus on the possible relationships between trace element imbalances and diseases; biological concentration of trace elements; variable relationships between trace elements in soils and vegetables; and trace element concentrations in mining areas. The ...
In this work, J.A. Chandler explains how local government in Britain has evolved from a structure that appeared to be relatively free from central government interference to, as John Prescott observes, 'one of the most centralised systems of government in the Western world'.