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Ageing is of perennial interest as a universal feature in all human societies. The genetic background and biochemical bases of ageing processes are currently being revealed in unprecedented detail. It is emerging that one of the main hurdles to be overcome in achieving a long and healthy lifespan is the maintenance of a properly functioning immune system. The main cause of death in people who have achieved "successful ageing" (which mostly means not having succumbed to cancer or cardiovascular disease) is infectious disease, caused by immunosenescence. This book contains chapters by many of the leaders in the field of immune-related issues in ageing and remediation.
This book covers a variety of topics in mechanics, with a special emphasis on material mechanics. It reports on fracture mechanics, fatigue of materials, stress-strain behaviours, as well as transferability problems and constraint effects in fracture mechanics. It covers different kind of materials, from metallic materials such as ferritic and austenitic steels, to composites, concrete, polymers and nanomaterials. Additional topics include heat transfer, quality control and reliability of structures and components. Furthermore, the book gives particular attention to new welding technologies such as STIR welding and spray metal coating, and to novel methods for quality control, such as Taguch...
This book is a printed edition of the Special Issue "Laser-Based Nano Fabrication and Nano Lithography" that was published in Nanomaterials
This authoritative handbook covers all aspects of immunosenescence, with contributions from experts in the research and clinical areas. It examines methods and models for studying immunosenescence; genetics; mechanisms including receptors and signal transduction; clinical relevance in disease states including infections, autoimmunity, cancer, metabolic syndrome, neurodegenerative diseases, frailty and osteoporosis; and much more.
"Natural Immunity" is a broadly-based account of the activities of the evolutionarily conserved molecules, cells and processes of the natural immune system. This encompasses the early host protection against microbes (bacteria and viruses) and tumours, prior to the generation of the adaptive immune response, diverse major current pathologies including inflammatory and autoimmune diseases, and key roles in essential physiological processes such as reproduction and wound healing. - The first comprehensive book on natural immunity - Reviews new topics, effects of behaviour, aging, and exercise, and diet on natural immunity - Highlights the physiological role of natural immunity - Focuses on the relationship of the neuroendocrine system with natural immunity - Brings together the diversity and complexity of natural immune system activity
Phoridae are probably the insect family with the greatest diversity of larval habits, but the least studied of the large families of flies due to identification difficulties. This book collates what is known about the natural history of the Phoridae world. It reviews eggs and oviposition, larval habits (including saprophages, kleptoparasites, fungus breeders, plant feeders, predator, parasitoids, parasites and enemies), pupae and their enemies, development, adult habits (including feeding, special associations, courtship, mating, phoretic mites and enemies) and ecological aspects. There follows a new user-friendly and extensively illustrated key to world genera and a review of the identification literature for each of the 229 genera recognized. A review of methods and an extensive bibliography complete the work.
This book constitutes the refereed proceedings of the 13th International Conference on Flexible Query Answering Systems, FQAS 2019, held in Amantea, Italy, in July 2019. The 27 full papers and 10 short papers presented were carefully reviewed and selected from 43 submissions. The papers present emerging research trends with a special focus on flexible querying and analytics for smart cities and smart societies in the age of big data. They are organized in the following topical sections: flexible database management and querying; ontologies and knowledge bases; social networks and social media; argumentation-based query answering; data mining and knowledge discovery; advanced flexible query answering methodologies and techniques; flexible query answering methods and techniques; flexible intelligent information-oriented and network-oriented approaches; big data veracity and soft computing; flexibility in tools; and systems and miscellanea.
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