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Vitamin D in Chronic Kidney Disease
Vitamin D deficiency, circulating levels lower than 15 ng/ml, is an epidemic disease worldwide with more than a billion people suffering of it in the beginning of the 21-century. Besides its impact on mineral and bone metabolism, these low vitamin D levels are also associated with a diversity of non-skeletal complications, among them cardiovascular disease, diabetes mellitus, multiple sclerosis, cancer, tuberculosis, and immune system dysfunction. Chronic Kidney Disease is also a very common disease, affecting more than 10% of the world population, ranging from stage 1 to stage 5 before dialysis. Approximately 1% of the population in industrialized countries is affected by end-stage renal disease (ESRD), needing a renal replacement therapy either hemodialysis or peritoneal dialysis, and ultimately by renal transplantation. Those CKD patients are more susceptible to exhibit reduced vitamin D stocks. Consequently, more than eighty percent of CKD patients have either insufficient or deficient vitamin D levels for multiple reasons.
Parathyroid Glands in Chronic Kidney Disease
This concise book provides practical strategies to help nephrologists and endocrinologists correctly diagnose and treat the various forms of parathyroid disease they may encounter in the management of chronic kidney disease. Each chapter deals with various topics related to parathyroid gland anatomy and physiology, as well as diagnostic tests and their particularities in regard to chronic disease. The book highlights the range of therapies used for the treatment of secondary hyperparathyroidism, and critically analyses the latest research in the field. Providing an up-to-date review of the current literature, including innovations in both medical and surgical treatment and current indications for parathyroidectomy, this practice-oriented book is an excellent resource for nephrologists, endocrinologists, endocrine surgeons and family medicine physicians.
Nephrology and Clinical Chemistry: The Essential Link
Clinical chemistry is a science that requires specific knowledge and teaching. The e-book covers several topics in clinical nephrology. Patients suffering from severe chronic kidney disease may be quasi asymptomatic. This lack of overt symptomatology sugg
Pathophysiology of Bone and Mineral Metabolism
Bone is the principal store for calcium and phosphate and one of the main regulators of mineral metabolism. The principal cells involved in bone remodeling are osteocytes, osteoblasts and osteoclasts, which maintain a precise equilibrium of bone mass. However, there are many factors that can affect bone and mineral homeostasis such as inadequate diet, microbiota alterations or aging. Furthermore, pathological conditions such as renal diseases, genetic disorders, obesity or inflammatory diseases can also potentially affect bone homeostasis, compromising bone health and leading to fractures and complications. Thus, integration of the mechanisms involved in mineral and bone alterations is key to understand bone physiology and its endocrine functions.
Tratado de Diálisis Peritoneal
Capítulos nuevos en esta edición: Contraindicaciones controvertidas para la diálisis peritoneal. Venciendo barreras en la selección de pacientes; La telemedicina aplicada a la diálisis; Hipertensión arterial en la enfermedad renal crónica, diálisis peritoneal y hemodiálisis; Patogenia y manejo de las alteraciones del metabolismo óseo y mineral en la enfermedad renal crónica; Cáncer en el paciente en diálisis. Con la colaboración de más de un centenar de expertos procedentes de España, Portugal, Francia, Hispanoamérica y Brasil. Nuevo y atractivo diseño, con numerosas tablas, cuadros e imágenes en color.
