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Oxidative Metabolism in Inflammation
Mitochondrial activity is involved in different functions such as cell proliferation, metabolism, Adenosine triphosphate (ATP) generation, and cell death. Particularly, mitochondria play a major role in inflammatory signaling. They regulate the activation, differentiation, and survival of macrophages, while changes in oxidative metabolism alter polarization. Mitochondria are the main source of free radicals, and macrophages increase their oxidative stress levels when they are active. The enhancement of free radicals generation in the mitochondria can damage healthy cells, leading to inflammation. Thus, several diseases associated with an increase in mitochondrial oxidative stress can be asso...
Environmental Stressors and OxInflammatory Tissues Responses
Environmental risk factors – noise, air pollution, chemical agents, and ultraviolet radiation – impact human health by contributing to the onset and progression of noncommunicable diseases. Accordingly, there is need for preclinical and clinical studies and comprehensive summary of major findings. This book is a state-of-the-art summary of these myriad severe life stressors. The chapters on the different pollutants focus on disease mechanisms (cardiovascular, neurological and metabolic disorders) and on oxidative stress and inflammation. The editors emphasize emerging mechanisms based on dysregulation of the circadian clock, the microbiome, epigenetic pathways, and cognitive function by environmental stressors, and introduce the exposome concept while highlighting existing research gaps. Key Features: Links various environmental stressors to the incidence of noncommunicable diseases Includes chapters on airborne toxins, chemical pollutants, noise, and ultraviolet radiation stressors Contributions from an international team of leading researchers Summarizes the impacts of stressors on disease mechanisms
Bioactive Lipids in Health and Disease
The purpose of this book is to introduce the readers on the perspective of the role that unsaturated fatty acids and complex lipids play on health and disease. Bioactive lipids can be modified affecting membrane composition, structure and fluidity in addition to changes in cell signaling associated to lipid-protein (membrane receptors) interactions, issues that are addressed by the authors. This book analyzes key topics involving bioactive lipids and their role in normal signaling and the mechanisms of disease. The book navigates from structural studies of oxidized and non-oxidized lipids to the reactions and cell signaling processes that bioactive lipids play in cardiovascular and neurodege...
LC-NMR
The isolation and structural characterization of substances present at very low concentrations, as is necessary to satisfy regulatory requirements for pharmaceutical drug degradants and impurities, can present scientific challenges. The coupling of HPLC with NMR spectroscopy has been at the forefront of cutting-edge technologies to address these issues. LC-NMR: Expanding the Limits of Structure Elucidation presents a comprehensive overview of key concepts in HPLC and NMR that are required to achieve definitive structure elucidation with very low levels of analytes. Because skill sets from both of these highly established disciplines are involved in LC-NMR, the author provides introductory ba...
Magnetic Oxides and Composites II
Magnetic oxides have highly interesting applications in the fields of permanent magnets, microwave devices, magnetic refrigeration, sensors, catalysis, and the health sector. This book focuses on the synthesis, characterization, and applications of various perovskites, garnets, manganites, carbon-based metal oxide nanocomposites, nanoferrites, and graphene-metal oxide nanocomposites. Keywords: Magnetic Oxides, Permanent Magnets, Microwave Devices, Magnetic Refrigeration, Sensors, Catalysis, Perovskites, Nanoferrites, Manganites, Rare Earth Iron Garnet, Graphene-Metal Oxide Nanocomposites, Carbon Nanomaterials, Mesoporous Materials, Nanocatalysts, Multifunctional Ferrites, Magnetocaloric Effect, Biosynthesis, Photo Catalysis, Antibacterial Activity, High Density Recording Media.
Immobilization of Enzymes and Cells
This fourth edition volume expands on the previous editions with new insights on important aspects to take into accounting when immobilizing enzymes and cells, illustrating outstanding examples that support those aspects, and exploring ways to fabricate and characterize heterogeneous biocatalysts including both immobilized enzymes and cells. The transformation of soluble and usually instable enzymes into heterogeneous and highly stable biocatalysts is strongly emphasized. The chapters in this book cover topics such as the importance of enzyme orientation on the support surface; application and characterization of immobilized enzymes; different functionalization chemistries for the modulation...
The Science of Flavonoids
This is the only book of its kind to provide an overview of the science of flavonoids in plants.
Composer Genealogies
Functioning as its own fully cross-referenced index, this volume lists composers and their dates, followed by their teachers and their notable students. A short introduction lays out the parameters by which composers were selected and provides a survey of the literature available for further study.
