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This is a timely review of the mechanisms underlying the presynaptic control of synaptic transmission and the role they play in sensory and motor behavior. Early chapters offer a detailed account of the anatomy, biophysics, and physiology of synaptic transmission at the peripheral and central synapses, focusing on the presynaptic control of transmitter release. Later chapters explore the organization of neural pathways leading to the presynaptic inhibition of transmitter release in segmental reflex pathways. A final section provides examples of the operation of presynaptic control mechanisms during specific sensory and motor functions in mammals, including humans. Integrating synaptic transmission and CNS functions at the systems level, this volume will be of particular interest to researchers studying both areas.
The Central Nervous System can be considered as an aggregate of neurons specialized in both the transmission and transformation of information. Information can be used for many purposes, but probably the most important one is to generate a representation of the "external" world that allows the organism to react properly to changes in its external environment. These functions range from such basic ones as detection of changes that may lead to tissue damage and eventual destruction of the organism and the implementation of avoidance reactions, to more elaborate representations of the external world implying recognition of shapes, sounds and textures as the basis of planned action or even refle...
This collection of contributions on the subject of the neural mechanisms of sensorimotor control resulted from a conference held in Cairns, Australia, September 3-6, 2001. While the three of us were attending the International Union of Physiological Sciences (IUPS) Congress in St Petersburg, Russia, in 1997, we discussed the implications of the next Congress being awarded to New Zealand. We agreed to organise a satellite to this congress in an area of mutual interest -the neuroscience of movement and sensation. Australia has a long-standing and enviable reputation in the field of neural mechanisms of sensorimotor control. Arguably this reached its peak with the award of a Nobel Prize to Sir ...
Presents the broad outline of NIH organizational structure, theprofessional staff, and their scientific and technical publications covering work done at NIH.
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This is a graduate-level text on the neurobiology of hearing, covering the structure and function of the central auditory pathway of all mammals.