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Contemporary Challenges in Autoimmunity, Volume 1173
This volume features key presentations from the 6th International Congress of Autoimmunity. The International Congress of Autoimmunity has become established as one of the major meetings in the field of immunology, with presentations covering every aspect of basic research in the hopes of clarifying pathogenesis of autoimmune disease as well as providing information on the latest innovations in biological and other modes of treatment. The goal of this volume is to present cutting edge research that focuses in particular on newer diagnostic tools and newer therapies for human autoimmune disease. NOTE: Annals volumes are available for sale as individual books or as a journal. For information on institutional journal subscriptions, please visit www.blackwellpublishing.com/nyas. ACADEMY MEMBERS: Please contact the New York Academy of Sciences directly to place your order (www.nyas.org). Members of the New York Academy of Science receive full-text access to the Annals online and discounts on print volumes. Please visit http://www.nyas.org/MemberCenter/Join.aspx for more information about becoming a member.
Italian Studies on Quality of Life
This volume provides an overview of the ways the Italian school of quality of life studies addresses well-being and quality of life, from both a substantive and a methodological point of view. It discusses various topics such as those of equitable and sustainable wellbeing, lifestyles, the organization of economy and welfare, as well as aspects related to the measurement of quality of life in small towns, institutional transparency and corruption prevention indicators. Chapters presented in this volume are drawn from papers presented at the conferences of the Italian Association for Quality of Life Studies (AIQUAV) held in Florence, Italy, in 2015 and 2016. The volume is organised into three parts. The first part is devoted to methods and indicators for research on quality of life, the second part to social sustainability, lifestyles, cultural aspects and local applications, and the third to economy, welfare and quality of life. The volume hosts contributions that are interdisciplinary in scope and mirror the complexity of the globalized world.
Mosaic of Autoimmunity
The Mosaic of Autoimmunity: The Novel Factors of Autoimmune Diseases describes the multifactorial origin and diversity of expression of autoimmune diseases in humans. The term implies that different combinations of factors in autoimmunity produce varying and unique clinical pictures in a wide spectrum of autoimmune diseases. Most of the factors involved in autoimmunity can be categorized into four groups: genetic, immune defects, hormonal and environmental factors. In this book, the environmental factors are reviewed, including infectious agents, vaccines as triggers of autoimmunity, smoking and its relationship with rheumatoid arthritis, systemic lupus erythematosus, thyroid disease, multiple sclerosis and inflammatory bowel diseases. An entirely new syndrome, the autoimmune/inflammatory syndrome induced by adjuvants (ASIA), is also included, along with other diseases that are now recognized as having an autoimmune etiopathogenesis.
Measuring and Understanding Complex Phenomena
Indicators are more and more applied to describe and analyze complex systems. Typical examples: Innovation potential of nations, child-well being, Environmental health, poverty, chemical pollution, corruption of nations. The task is: How can a system of indicators be defined in order to fulfill the above expectations. One possibility is the application of the mathematical theory of partial order, especially when the indicator system shall be used for ranking purposes.
Immunology of Psoriatic Disease
Psoriasis is a chronically relapsing inflammatory skin disorder affecting about 2% of the worldwide population. The disease is associated with important systemic manifestations, including cardiovascular comorbidities and metabolic syndrome. In addition, about 30% of patients develop joint inflammation known as psoriatic arthritis (PsA). Our knowledge on the pathogenesis of psoriasis has dramatically expanded in the last decade, suggesting the existence (or co-existence) of both auto-immune and auto-inflammatory components. Skin lesions develop from a complex interplay between keratinocytes, vascular endothelium, dendritic cells, and T cells, generating a self-sustaining inflammatory cycle. W...
Geluk
Hoe kunnen we vandaag, ondanks alles, toch nog een beetje gelukkig en hoopvol blijven? Onderzoeker Leo Bormans vroeg het opnieuw aan 100 topexperts uit 50 landen, meer dan tien jaar na de eerste editie van deze wereldwijde bestseller. Nieuwe Tijden vragen om Nieuwe Antwoorden. Het virus, de oorlog, het klimaat, armoede en eenzaamheid maken mensen onzeker. Nu de tijden wankel zijn, is er echter meer dan ooit interesse voor wat belangrijk is in het leven. Wat hebben de gelukwetenschappers ondertussen ontdekt? Ze werden uitgedaagd om hun nieuwe inzichten samen te vatten in één zin: de essentie. Daar voegen ze de kern van hun onderzoek én zes concrete adviezen aan toe. Een inspirerende gids v...
Complexity of Social Phenomena
What is complexity? What are the characteristics of a complex system? What does it mean to measure? How to develop an efficient tool for measuring socio-economic phenomena? What is synthesis? What are the main statistical tools for synthesis of multi-indicator systems? These are the research questions that are attempted to be answered in this book, the result of the author’s research work during his PhD. The book offers a conceptual and methodological analysis of the topic of synthesis of complex social phenomena, also proposing interesting applications to real cases. Winner of the Competition “Prize for PhD Thesis 2020” arranged by Sapienza University Press.
