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Gastrointestinal (GI) cancer, the group of cancers that affect the gastrointestinal tract and other organs that are contained within the digestive system, including the esophagus, pancreas, stomach, colon, rectum, anus, liver, biliary system and small intestine, is the most common malignant diseases with high mortality rates, leading to a substantial burden on public health and healthcare systems around the world. Diverse subtypes of GI cancer impressively exhibit similar characteristics like high frequency oncogenic mutation burden, early metastatic potency, chemo-resistance and immunotherapeutic tolerance indicating a possible unique tumorigenic mechanism.
Foreword from the Editor: With the second installment in the Quarterly Highlights series, Frontiers in Oncology has once again had a strong quarter, and continues to publish important research, with submissions from across the globe - and readership from across the globe. In this quarter, we saw a number of different impact metrics become updated using recent data. The 2019 impact metrics reflect our competitive and respectable status in the field and amongst competitors. We find it very encouraging to see that our impact has remained high, and thank the entirety of the Editorial Board and Office for their contributions and hard work in doing so. Once again with a record-breaking number of p...
Dieses Buch vermittelt die optimale Grundlage für die Ausbildung und Praxis in der ganzheitlichen und kausalen Diagnostik und Therapie nach F.X. Mayr. Die F.X. Mayr-Medizin bietet eine sehr sensible Diagnostik, die Abweichungen vom idealen Gesundheitszustand lange vor Ausbruch einer manifesten Erkrankung entdecken kann. Aktuelle Themen wie Diagnostik und Therapie von Silent-Inflammation, Leaky-Gut-, Maldigestion- und Reizdarmsyndrom werden ebenso besprochen wie chronisch entzündlicher Darmerkrankungen, Nahrungsmittelintoleranzen, Mikrobiom-Dysbalance, Stoffwechselentgleisungen als auch mitochondriale Dysfunktion. Die Therapie wird auf Basis der 4 Säulen Schonung, Säuberung, Schulung und ...
Starting in the early 1970s, a type of programmed cell death called apoptosis began to receive attention. Over the next three decades, research in this area continued at an accelerated rate. In the early 1990s, a second type of programmed cell death, autophagy, came into focus. Autophagy has been studied in mammalian cells for many years. The recen