Welcome to our book review site go-pdf.online!
You may have to Search all our reviewed books and magazines, click the sign up button below to create a free account.
Inflammation and tendon healing
Tendons heal through three different overlapping phases; the inflammatory, proliferative and remodeling phase. Many studies have investigated what factors influence healing of tendons. However, little was known about inflammation and the immune cells present during Achilles tendon healing by the time this thesis started. We developed a flow cytometry method for our rat model of tendon healing, which enabled us to study different leukocyte subpopulations during Achilles tendon healing. The general aim of this thesis was to understand more about inflammation and the immune cell populations present during tendon healing and how the immune cell composition changes during normal tendon healing. M...
Aseptic Loosening of Orthopedic Implants
Aseptic loosening is the main cause of failure of orthopedic prostheses. With no pharmaceuticals to prevent or mitigate periprosthetic bone degradation, a surgery to replace the loose implant with a new one is the only choice to restore patients’ function. Most studies on mechanisms for aseptic loosening investigate wear debris particle-induced osteolysis. However, pathological loading conditions around unstable implants can also trigger osteoclast differentiation and bone loss. In the first study, global gene expression changes induced by mechanical instability of implants, and by titanium particles were compared in a validated rat model for aseptic loosening. Microarray analysis showed t...
Organic Bioelectronics for Neurotransmitter Release at the Speed of Life
The signaling dynamics in neuronal networks includes processes ranging from lifelong neuromodulation to direct synaptic neurotransmission. In chemical synapses, the time delay it takes to pass a signal from one neuron to the next lasts for less than a millisecond. At the post-synaptic neuron, further signaling is either up- or down-regulated, dependent on the specific neurotransmitter and receptor. While this up- and down-regulation of signals usually runs perfectly well and enables complex performance, even a minor dysfunction of this signaling system can cause major complications, in the shape of neurological disorders. The field of organic bioelectronics has the ability to interface neuro...
Tendon Healing
Mechanical loading and the inflammatory response during tendon healing might be important for the healing process. Mechanical loading can improve the healing tendon but the mechanism is not fully understood. The aim of this thesis was to further clarify the effect of mechanical loading on tendon healing and how mechanical loading affects the inflammatory response during the healing process. We used a rat Achilles tendon model to study healing. The rats were exposed to different degrees of loading by unloading methods such as paralysis of the calf muscles with Botox, tail suspension, and an orthosis (a boot). Full loading was achieved by free cage activity or treadmill walking. Microdamage in...
Bone and Cartilage Regeneration
This invaluable resource discusses clinical applications with effects and side-effects of applications of stem cells in bone and cartilage regeneration. Each chapter is contributed by a pre-eminent scientist in the field and covers such topics as skeletal regeneration by mesenchymal stem cells, clinical improvement of mesenchymal stem cell injection in injured cartilage and osteoarthritis, Good manufacturing practice (GMP), minimal critera of stem cells for clinical applications, future directions of the discussed therapies and much more. Bone & Cartilage Regeneration and the other books in the Stem Cells in Clinical Applications series will be invaluable to scientists, researchers, advanced students and clinicians working in stem cells, regenerative medicine or tissue engineering.
Early Osteoarthritis
Early osteoarthritis is novel topic for orthopedic surgeons and its process begins immediately after joint injury. The mechanical restoration of the joint surface or ligamentous stability is not sufficient to restore the homeostatic environment in the joint, and this leads to osteoarthritis, despite mechanical stability and alignment. This book sheds light on the various mechanisms and systems involved in the gradual decline of the injured joint toward manifest osteoarthritis. Published in collaboration with ISAKOS, this volume appeals to all stakeholders in surgical orthopaedics and sports medicine.
Reverse Shoulder Arthroplasty
The definitive book on reverse shoulder arthroplasty from leading orthopaedic shoulder surgeons This masterful book from top experts provides clinical insights on reverse shoulder arthroplasty gleaned from hands-on refinement of shoulder replacement techniques. Years of significant biomechanical and clinical research yielded invaluable knowledge that led to important improvements in functional outcome and implant durability. Among these refinements were stronger polyethylene derivatives, better ingrowth technology, and improved connection devices. As the durability and longevity of implant technology increased, younger active patients became suitable candidates for this procedure. In fact, R...
Orthopaedic Basic Science: Foundations of Clinical Practice
Publisher's Note: Products purchased from 3rd Party sellers are not guaranteed by the Publisher for quality, authenticity, or access to any online entitlements included with the product. Build your Foundation of Basic Science – from Research to Clinical Application A great tool for MOC preparation! A 'must have' for residency! This fourth edition, developed in a partnership between the American Academy of Orthopaedic Surgeons (AAOS) and the Orthopaedic Research Society (ORS), is your concise and clinically relevant resource for the diagnosis and treatment of musculoskeletal diseases and conditions.
Temperature Regulation in Laboratory Rodents
With the help of extensive data tables and figures, this book explains the key facets of rodent thermal physiology, including neurological control and gender and intraspecies variations. The book should therefore find use in government, academic or industrial laboratories whose researchers are working with rodents.
