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Introduction -- Defining the public interest in the US and European patent systems -- Confronting the questions of life-form patentability -- Commodification, animal dignity, and patent-system publics -- Forging new patent politics through the human embryonic stem cell debates -- Human genes, plants, and the distributive implications of patents -- Conclusion
Vitamin E is a fat-soluble vitamin that exists in eight different forms. Each form has its own biological activity, which is the measure of potency or functional use in the body. Alpha-tocopherol (-tocopherol) is the name of the most active form of vitamin E in humans. It is also a powerful biological antioxidant. Vitamin E in supplements is usually sold as alpha-tocopheryl acetate, a form that protects its ability to function as an antioxidant. The synthetic form is labelled 'D, L' while the natural form is labelled 'D'. The synthetic form is only half as active as the natural form. Antioxidants such as vitamin E act to protect the cells against the effects of free radicals, which are poten...
One of the major biomedical triumphs of the post-World War II era was the defmitive demonstration that hypercholesterolemia is a key causative factor in atherosclerosis; that hypercholesterolemia can be effectively treated; and that treatment significantly reduces not only coronary disease mortality but also all cause mortality. Treatment to lower plasma levels of cholesterol - primarily low density lipoprotein (LDL) cholesterol - is now accepted as best medical practice and both physicians and patients are being educated to take aggressive measures to lower LDL. We can confidently look forward to important decreases in the toll of coronary artery disease over the coming decades. However, th...
Vols. for 1963- include as pt. 2 of the Jan. issue: Medical subject headings.
This volume constitutes the refereed proceedings of the 9th International Symposium on Experimental Algorithms, SEA 2010, held on Ischia Island, Naples, Italy, in May 2010. The 40 revised full papers presented together with two invited papers were carefully reviewed and selected from 73 submissions. The topics covered include algorithm engineering, algorithmic libraries, algorithmic mechanism design, analysis of algorithms, algorithms for memory hierarchies, approximation techniques, bioinformatics, branch and bound algorithms, combinatorial and irregular problems, combinatorial structures and graphs, communication networks, complex networks, computational geometry, computational learning theory, computational optimization, computer systems, cryptography and security, data streams, data structures, distributed and parallel algorithms, evaluation of algorithms for realistic environments, experimental techniques and statistics, graph drawing, heuristics for combinatorial optimization
Mechanical ventilation is a life-saving procedure that has been used for decades to treat patients with respiratory failure. In recent years there have been major advances in our understanding of how to ventilate patients, when to initiate and discontinue ventilation, and importantly, the side effects of mechanical ventilation. This book represents a state-of-the-art review by the leading experts in this field and covers a number of important topics including epidemiology, underlying physiological concepts, and approaches to monitoring. The pros and cons of various modes of ventilation are reviewed, as are novel forms of ventilation that may play a role in the future management of patients with respiratory failure. The importance of patient-ventilator synchrony and ventilator-induced lung injury are reviewed, with a focus on recent clinical trials and the challenges of implementing the results into clinical practice.
Each volume of Advances in Pharmacology provides a rich collection of reviews on timely topics. Emphasis is placed on the molecular bases of drug action, both applied and experimental. This volume contains chapters that address diverse but interrelated areas pertaining to the chemistry, biochemistry, molecular biology, and pharmacology of nitric oxide in mammalian cells. The contents form a comprehensive treatise of factors influencing the control of nitric oxide production in various cell types. - Presents comprehensive coverage of the chemical properties of nitric oxide and how they form the basis for the multifaceted biological actions for nitric oxide - Contains the most current and detailed documentation of the properties and regulation of nitric oxide synthases - Provides the most up-to-date review of inhalational nitric oxide therapy for treatment of respiratory dysfunction
During the past decade, experimental and clinical studies have suggested that dyslipidemia may be an important risk factor for the progression of renal disease. This volume explores in great detail recent advances in our understanding of the pathogenesis and treatment of this common complication of progressive renal injury. In the experimental investigations presented, emphasis is placed on specific disturbances of lipids that are seen in progressive renal disease including the effects of oxidatively modified lipoproteins and Lp(a) on various functions of the glomerular cells. Clinical studies have identified dyslipidemia as a risk factor for progressive renal disease in diabetes mellitus, v...